Plasmodium yoelii: the effect of second blood meal and anti-sporozoite antibodies on development and gene expression in the mosquito vector, Anopheles stephensi

L. F. Lopes; P. Abrantes; A. P. Silva; V. E. doRosario; H. Silveira

doi:10.1016/j.exppara.2006.09.007

Plasmodium yoelii: the effect of second blood meal and anti-sporozoite antibodies on development and gene expression in the mosquito vector, Anopheles stephensi

L. F. Lopes, P. Abrantes, A. P. Silva, V. E. doRosario, H. Silveira

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

The sporogonic development of the malaria parasite takes place in the mosquito and a wide range of factors modulates it. Among those, the contents of the blood meal can influence the parasite development directly or indirectly through the mosquito response to the infection. We have studied the effect of a second blood meal in previously infected mosquitoes and the effect of anti-sporozoite immune serum on parasite development and mosquito response to the infection. The prevalence and intensity of infection and gene expression of both Plasmodium yoelii and Anopheles stephensi was analyzed. We verified that a second blood meal and its immune status interfere with parasite development and with Plasmodium and mosquito gene expression.

Original language	English
Pages (from-to)	259-269
Number of pages	11
Journal	Experimental Parasitology
Volume	115
Issue number	3
DOIs	https://doi.org/10.1016/j.exppara.2006.09.007
Publication status	Published - 1 Mar 2007

Keywords

α-[P]dATP
4-aminobenzoic acid
5′-[α
P] triphosphate
Anopheles stephensi
Apicomplexa
circumsporozoite protein
CS
DDRT-PCR
deoxyadenosine
deoxyribonucleic acid
deoxyribonucleotide triphosphate
differential display reverse transcriptase PCR
dithiothreitol
DNA
dNTP
DTT
IFA
IFN-γ
IgG
IHMT
Immune serum
immunoglobulin G
indirect fluorescent antibody
Instituto de Higiene e Medicina Tropical
interferon γ
Malaria
MMLV-RT
Moloney murine leukemia virus reverse transcriptase
nitric oxide
NO
PABA
PCR
Plasmodium yoelii
polymerase chain reaction
QT-PCR
quantitative real time PCR analysis
restriction fragment length polymorphism
RFLP
ribonucleic acid
RNA
Sporogonic development
TGF-β1
TNF-α
transport RNA
tRNA
tumor necrosis factor α
Tumor necrosis factor β one

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.exppara.2006.09.007

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title = "Plasmodium yoelii: the effect of second blood meal and anti-sporozoite antibodies on development and gene expression in the mosquito vector, Anopheles stephensi",

abstract = "The sporogonic development of the malaria parasite takes place in the mosquito and a wide range of factors modulates it. Among those, the contents of the blood meal can influence the parasite development directly or indirectly through the mosquito response to the infection. We have studied the effect of a second blood meal in previously infected mosquitoes and the effect of anti-sporozoite immune serum on parasite development and mosquito response to the infection. The prevalence and intensity of infection and gene expression of both Plasmodium yoelii and Anopheles stephensi was analyzed. We verified that a second blood meal and its immune status interfere with parasite development and with Plasmodium and mosquito gene expression.",

keywords = "α-[P]dATP, 4-aminobenzoic acid, 5′-[α, P] triphosphate, Anopheles stephensi, Apicomplexa, circumsporozoite protein, CS, DDRT-PCR, deoxyadenosine, deoxyribonucleic acid, deoxyribonucleotide triphosphate, differential display reverse transcriptase PCR, dithiothreitol, DNA, dNTP, DTT, IFA, IFN-γ, IgG, IHMT, Immune serum, immunoglobulin G, indirect fluorescent antibody, Instituto de Higiene e Medicina Tropical, interferon γ, Malaria, MMLV-RT, Moloney murine leukemia virus reverse transcriptase, nitric oxide, NO, PABA, PCR, Plasmodium yoelii, polymerase chain reaction, QT-PCR, quantitative real time PCR analysis, restriction fragment length polymorphism, RFLP, ribonucleic acid, RNA, Sporogonic development, TGF-β1, TNF-α, transport RNA, tRNA, tumor necrosis factor α, Tumor necrosis factor β one",

author = "Lopes, {L. F.} and P. Abrantes and Silva, {A. P.} and doRosario, {V. E.} and H. Silveira",

year = "2007",

month = mar,

day = "1",

doi = "10.1016/j.exppara.2006.09.007",

language = "English",

volume = "115",

pages = "259--269",

journal = "Experimental Parasitology",

issn = "0014-4894",

publisher = "Elsevier Science B.V., Amsterdam.",

number = "3",

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T1 - Plasmodium yoelii

T2 - the effect of second blood meal and anti-sporozoite antibodies on development and gene expression in the mosquito vector, Anopheles stephensi

AU - Lopes, L. F.

AU - Abrantes, P.

AU - Silva, A. P.

AU - doRosario, V. E.

AU - Silveira, H.

PY - 2007/3/1

Y1 - 2007/3/1

N2 - The sporogonic development of the malaria parasite takes place in the mosquito and a wide range of factors modulates it. Among those, the contents of the blood meal can influence the parasite development directly or indirectly through the mosquito response to the infection. We have studied the effect of a second blood meal in previously infected mosquitoes and the effect of anti-sporozoite immune serum on parasite development and mosquito response to the infection. The prevalence and intensity of infection and gene expression of both Plasmodium yoelii and Anopheles stephensi was analyzed. We verified that a second blood meal and its immune status interfere with parasite development and with Plasmodium and mosquito gene expression.

AB - The sporogonic development of the malaria parasite takes place in the mosquito and a wide range of factors modulates it. Among those, the contents of the blood meal can influence the parasite development directly or indirectly through the mosquito response to the infection. We have studied the effect of a second blood meal in previously infected mosquitoes and the effect of anti-sporozoite immune serum on parasite development and mosquito response to the infection. The prevalence and intensity of infection and gene expression of both Plasmodium yoelii and Anopheles stephensi was analyzed. We verified that a second blood meal and its immune status interfere with parasite development and with Plasmodium and mosquito gene expression.

KW - α-[P]dATP

KW - 4-aminobenzoic acid

KW - 5′-[α

KW - P] triphosphate

KW - Anopheles stephensi

KW - Apicomplexa

KW - circumsporozoite protein

KW - CS

KW - DDRT-PCR

KW - deoxyadenosine

KW - deoxyribonucleic acid

KW - deoxyribonucleotide triphosphate

KW - differential display reverse transcriptase PCR

KW - dithiothreitol

KW - DNA

KW - dNTP

KW - DTT

KW - IFA

KW - IFN-γ

KW - IgG

KW - IHMT

KW - Immune serum

KW - immunoglobulin G

KW - indirect fluorescent antibody

KW - Instituto de Higiene e Medicina Tropical

KW - interferon γ

KW - Malaria

KW - MMLV-RT

KW - Moloney murine leukemia virus reverse transcriptase

KW - nitric oxide

KW - NO

KW - PABA

KW - PCR

KW - Plasmodium yoelii

KW - polymerase chain reaction

KW - QT-PCR

KW - quantitative real time PCR analysis

KW - restriction fragment length polymorphism

KW - RFLP

KW - ribonucleic acid

KW - RNA

KW - Sporogonic development

KW - TGF-β1

KW - TNF-α

KW - transport RNA

KW - tRNA

KW - tumor necrosis factor α

KW - Tumor necrosis factor β one

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UR - https://www.sciencedirect.com/science/article/abs/pii/S0014489406002153?via%3Dihub

U2 - 10.1016/j.exppara.2006.09.007

DO - 10.1016/j.exppara.2006.09.007

M3 - Article

C2 - 17083935

AN - SCOPUS:37849188525

SN - 0014-4894

VL - 115

SP - 259

EP - 269

JO - Experimental Parasitology

JF - Experimental Parasitology

IS - 3

ER -

Plasmodium yoelii: the effect of second blood meal and anti-sporozoite antibodies on development and gene expression in the mosquito vector, Anopheles stephensi

Abstract

Keywords

UN SDGs

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