Plasmodium species mixed infections in two areas of Manhiça district, Mozambique

P. X. Marques, F. Saúte, V. V. Pinto, S Cardoso, J. Pinto, Pedro L. Alonso, V. E. Rosário, A. P. Arez

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

We compared the distribution patterns of individual Plasmodium species and mixed-species infections in two geographically close endemic areas, but showing environmental differences. Comparisons concerned circulating Plasmodium infections in both human and mosquito vector populations in the dry and wet seasons, at a micro-epidemiological level (households). Both areas revealed a very high overall prevalence of infection, all year-round and in all age groups. Plasmodium falciparum was the predominant species, being found in the vast majority of infected individuals regardless of the presence of other species. Plasmodium malariae and Plasmodium ovale occurred almost exclusively in mixed infections. Seasonal variation in P. malariae prevalence was observed in one area but not in the other. A decrease in P. malariae prevalence concurred with a marked increase of P. falciparum prevalence. However this was strongly dependent on age and when analysing infections at the individual level, a different pattern between co-infecting species was unveiled. Regarding transmission patterns, in both areas, P. falciparum gametocytes predominated in single infections regardless of age and P. malariae gametocyte carriage increased when its overall prevalence decreased.

Original languageEnglish
Pages (from-to)96-102
Number of pages7
JournalInternational journal of biological sciences
Volume1
Issue number3
DOIs
Publication statusPublished - 1 May 2005

Keywords

  • Preschool child
  • Season
  • Adolescent
  • Animal
  • Article
  • Child
  • Human
  • Infant
  • Plasmodium falciparum
  • Isolation and purification
  • Malaria
  • Mosquito
  • Mozambique
  • Parasitology
  • Prevalence
  • Plasmodium ovale
  • Polymerase chain reaction

UN Sustainable Development Goals (SDGs)

  • SDG 3 - Good Health and Well-Being

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