Hybrid photodiodes (HPD) systems are on the rise. The growing interest on these devices is mainly due to their power in image sensing and bioengineering solutions. In this work, a new class of donor-acceptor dendrimers was synthesized and incorporated, along with a ruthenium sensitizer dye, into low cost devices comprised of one single layer of a biocompatible matrix (agarose). Exploring different electrodes, low current devices with a counter-electrode dependent response have been successfully assembled at room temperature. Using a stainless steel electrode, sensitized donor-acceptor dendrimers provide photodiode-like systems having nA dark currents.