Phenylpropanoid saccharide esters, methods and uses thereof

Krasimira Todorova Markova-Petrova; Isabel Cristina Fernandes Rodrigues  Ferreira; Manuel Ricardo Costa  Calhelha; Marina Sokovic

Phenylpropanoid saccharide esters, methods and uses thereof

Krasimira Todorova Markova-Petrova (Inventor), Isabel Cristina Fernandes Rodrigues Ferreira (Inventor), Manuel Ricardo Costa Calhelha (Inventor), Marina Sokovic (Inventor)

Research output: Patent › Regional/Other National Application

Abstract

The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicrobial agents, cytotoxic agents and/or antitumoral agents. The present disclosure relates to a compound for formula I wherein R1, R2, R3 and R4 are independently selected from each other; R1 is selected from H or COCH3, R2, R3 and R4 is selected from H, OCH3, OH, for use in a method for the treatment of a microbial infection, or for use in a method for the treatment of a fungal infection or for use in a method for the treatment of cancer.

Original language	English
Patent number	EP3938374
IPC	C07H 15/ 04 A I, A61K31/7024, A61K31/7028, A61P31/00, A61P31/04,A61P31/10,A61P33/00
Priority date	14/03/19
Filing date	14/10/21
Publication status	Published - 19 Jan 2022

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Phenylpropanoid saccharide esters, methods and uses thereof",

abstract = "The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicrobial agents, cytotoxic agents and/or antitumoral agents. The present disclosure relates to a compound for formula I wherein R1, R2, R3 and R4 are independently selected from each other; R1 is selected from H or COCH3, R2, R3 and R4 is selected from H, OCH3, OH, for use in a method for the treatment of a microbial infection, or for use in a method for the treatment of a fungal infection or for use in a method for the treatment of cancer.",

author = "Markova-Petrova, {Krasimira Todorova} and Ferreira, {Isabel Cristina Fernandes Rodrigues} and Calhelha, {Manuel Ricardo Costa} and Marina Sokovic",

year = "2022",

month = jan,

day = "19",

language = "English",

type = "Patent",

note = "EP3938374; C07H 15/ 04 A I, A61K31/7024, A61K31/7028, A61P31/00, A61P31/04,A61P31/10,A61P33/00",

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TY - PAT

T1 - Phenylpropanoid saccharide esters, methods and uses thereof

AU - Markova-Petrova, Krasimira Todorova

AU - Ferreira, Isabel Cristina Fernandes Rodrigues

AU - Calhelha, Manuel Ricardo Costa

AU - Sokovic, Marina

PY - 2022/1/19

Y1 - 2022/1/19

N2 - The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicrobial agents, cytotoxic agents and/or antitumoral agents. The present disclosure relates to a compound for formula I wherein R1, R2, R3 and R4 are independently selected from each other; R1 is selected from H or COCH3, R2, R3 and R4 is selected from H, OCH3, OH, for use in a method for the treatment of a microbial infection, or for use in a method for the treatment of a fungal infection or for use in a method for the treatment of cancer.

AB - The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicrobial agents, cytotoxic agents and/or antitumoral agents. The present disclosure relates to a compound for formula I wherein R1, R2, R3 and R4 are independently selected from each other; R1 is selected from H or COCH3, R2, R3 and R4 is selected from H, OCH3, OH, for use in a method for the treatment of a microbial infection, or for use in a method for the treatment of a fungal infection or for use in a method for the treatment of cancer.

M3 - Regional/Other National Application

M1 - EP3938374

Y2 - 2021/10/14

ER -

Phenylpropanoid saccharide esters, methods and uses thereof

Abstract

UN SDGs

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