Phenylpropanoid Saccharide Esters, Methods and Uses Thereof

Krasimira Todorova Markova Petrova (Inventor), Isabel Ferreira (Inventor), Ricardo Calhelha (Inventor), Marina Sokovic (Inventor)

Research output: PatentInternational PCT application

Abstract

The present disclosure relates to phenylpropanoid saccharide esters, methods for the synthesis of libraries of phenylpropanoid saccharide esters with different degree and place of substitution in the sugar core, and their use as antimicrobial agents, cytotoxic agents and/or antitumoral agents. The present disclosure relates to a compound for formula I wherein R1, R2, R3 and R4 are independently selected from each other; R1 is selected from H or COCH3, R2, R3 and R4 is selected from H, OCH3, OH, for use in a method for the treatment of a microbial infection, or for use in a method for the treatment of a fungal infection or for use in a method for the treatment of cancer.
Original languageEnglish
Patent numberWO/2020/183442
IPCC07H 13/04 2006.01, A61K31/7024, A61K31/7028,A61P31/00, A61P31/04, A61P31/10, A61P33/00
Priority date14/03/19
Filing date16/03/20
Publication statusPublished - 17 Sept 2020

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