Phaeohyphomycosis caused by Alternaria infectoria presenting as multiple vegetating lesions in a renal transplant patient

Daniela Cunha, Cristina Amaro, María Raquel Vieira, María da Luz Martins, Ana Paula Maduro, João Inácio, Ana Afonso, Gabriela Marques Pinto, Jorge Cardoso

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The genus Alternaria is one of the most common black moulds and appears to be increasing as a causative agent of subcutaneous phaeohyphomycosis, particularly among immunosuppressed patients. A 53-year-old patient who had received a kidney transplant presented with multiple verrucous lesions on the distal extremities. Positive histopathology and cultures, in addition to rDNA ITS region sequencing, identified the fungal isolate as Alternaria infectoria. Oral itraconazole was administered for 10 months. A follow-up at 15 months demonstrated no signs of infection. Clinical manifestations of cutaneous alternariosis vary significantly and only a few cases have been described in the literature. Although optimal treatment options remain controversial, this case of phaeohyphomycosis was successfully treated with itraconazole monotherapy.

Original languageEnglish
Pages (from-to)44-46
Number of pages3
JournalRevista Iberoamericana de Micologia
Volume29
Issue number1
DOIs
Publication statusPublished - 1 Jan 2012

Keywords

  • Immunocompromised patient
  • Itraconazole
  • Kidney transplantation
  • Mycosis

UN Sustainable Development Goals (SDGs)

  • SDG 3 - Good Health and Well-Being

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