TY - JOUR
T1 - pH-Dependent Crystallization of 2-, 4-, 5-, and 6-Hydroxynicotinic Acids in Aqueous Media
AU - Johnson, Aidan V.
AU - Piedade, M. Fátima M.
AU - Esteves, Catarina V.
N1 - Funding Information:
This research was funded by Fundação para a Ciência e a Tecnologia (FCT), Portugal (projects PTDC/QUIOUT/28401/2017, LISBOA-01-0145-FEDER-028401, UIDB/00100/2020, UIDP/00100/2020, and LA/P/0056/2020).
Publisher Copyright:
© 2023 by the authors.
PY - 2023/7/5
Y1 - 2023/7/5
N2 - 2-, 4-, 5-, and 6-hydroxynicotinic acids were crystallized in a pH-dependent manner using only water as the preferred solvent. The crystallization outcome was quite diverse: individual crystals of different sizes and shapes, microcrystalline powders, crystalline aggregates, and almost amorphous solids. Such a variety of solid forms demonstrates the relevance of pH control during crystallization processes.
AB - 2-, 4-, 5-, and 6-hydroxynicotinic acids were crystallized in a pH-dependent manner using only water as the preferred solvent. The crystallization outcome was quite diverse: individual crystals of different sizes and shapes, microcrystalline powders, crystalline aggregates, and almost amorphous solids. Such a variety of solid forms demonstrates the relevance of pH control during crystallization processes.
KW - 2-, 4-, 5-, and 6-hydroxynicotinic acids
KW - crystallization
KW - pH control
UR - http://www.scopus.com/inward/record.url?scp=85166212549&partnerID=8YFLogxK
U2 - 10.3390/cryst13071062
DO - 10.3390/cryst13071062
M3 - Article
AN - SCOPUS:85166212549
SN - 2073-4352
VL - 13
JO - Crystals
JF - Crystals
IS - 7
M1 - 1062
ER -