Pd-catalysed amination on a soluble polymer support: arylation of anilines with PEG-supported aryl halides

Luísa da Conceição Costa Raínho de Carvalho, Marina J. Dias Pires, Eduarda Fernandes, Mónica Manuel B. Marques

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

PEG supported aryl halides were found to serve as substrates for the Pd-catalysed N-arylation of several substituted anilines and alkyl amines under solventless conditions. Moreover, the Pd2dba3/XPhos catalyst system enabled the coupling reactions to take place smoothly with excellent yields under a low catalyst loading (1 mol% Pd and 3 mol% ligand). © 2013 The Royal Society of Chemistry.
Original languageEnglish
Pages (from-to)25711-25715
JournalRSC Advances
Volume3
Issue number48
DOIs
Publication statusPublished - 28 Dec 2013

Keywords

  • SOLID-PHASE SYNTHESIS
  • POLY(ETHYLENE GLYCOL)
  • POLYETHYLENE-GLYCOL
  • BENZIMIDAZOLES
  • SOLVENT
  • SYSTEM
  • AMINES
  • MEDIA
  • RESIN
  • CROSS

Fingerprint Dive into the research topics of 'Pd-catalysed amination on a soluble polymer support: arylation of anilines with PEG-supported aryl halides'. Together they form a unique fingerprint.

  • Cite this