TY - JOUR
T1 - Patterns of transmitted HIV drug resistance in Europe vary by risk group
AU - Frentz, Dineke
AU - Van De Vijver, David
AU - Abecasis, Ana
AU - Albert, Jan
AU - Hamouda, Osamah
AU - Jørgensen, Louise
AU - Kücherer, Claudia
AU - Struck, Daniel
AU - Schmit, Jean Claude
AU - Vercauteren, Jurgen
AU - Åsjö, Birgitta
AU - Balotta, Claudia
AU - Bergin, Colm
AU - Beshkov, Danail
AU - Camacho, Ricardo
AU - Clotet, Bonaventura
AU - Griskevicius, Algirdas
AU - Grossman, Zehava
AU - Horban, Andrzej
AU - Kolupajeva, Tatjana
AU - Korn, Klaus
AU - Kostrikis, Leondios
AU - Linka, Kirsi Liitsola Marek
AU - Nielsen, Claus
AU - Otelea, Dan
AU - Paraskevis, Dimitrios
AU - Paredes, Roger
AU - Poljak, Mario
AU - Puchhammer-Stöckl, Elisabeth
AU - Sönnerborg, Anders
AU - Stanekova, Danica
AU - Stanojevic, Maja
AU - Vandamme, Anne Mieke
AU - Boucher, Charles
AU - Wensing, Annemarie
N1 - PMID:24721998
WOS:000336909100083
PY - 2014/4/10
Y1 - 2014/4/10
N2 - Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the risk behaviour reported. Methods: HIV-1 patients newly diagnosed in 27 countries from 2002 through 2007 were included. Inclusion was representative for risk group and geographical distribution in the participating countries in Europe. Trends over time were calculated by logistic regression. Results: From the 4317 patients included, the majority was men-having-sex-with-men -MSM (2084, 48%), followed by heterosexuals (1501, 35%) and injection drug users (IDU) (355, 8%). MSM were more often from Western Europe origin, infected with subtype B virus, and recently infected (
AB - Background: In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the risk behaviour reported. Methods: HIV-1 patients newly diagnosed in 27 countries from 2002 through 2007 were included. Inclusion was representative for risk group and geographical distribution in the participating countries in Europe. Trends over time were calculated by logistic regression. Results: From the 4317 patients included, the majority was men-having-sex-with-men -MSM (2084, 48%), followed by heterosexuals (1501, 35%) and injection drug users (IDU) (355, 8%). MSM were more often from Western Europe origin, infected with subtype B virus, and recently infected (
UR - http://www.scopus.com/inward/record.url?scp=84899537490&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0094495
DO - 10.1371/journal.pone.0094495
M3 - Article
C2 - 24721998
AN - SCOPUS:84899537490
VL - 9
JO - PlosOne
JF - PlosOne
SN - 1932-6203
IS - 4
M1 - e94495
ER -