On the reactivity of mRNA Cap0: C-H oxidative addition of 7-methylguanosine to Pt and base pairing studies

Maria Inês P.S. Leitão, Carmen González, Giulia Francescato, Zuzanna Filipiak, Ana Petronilho

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

7-Methylguanosine, whose lability to form an ylide/NHC has been known for decades, reacts with [Pt(PPh3)4] via C-H oxidative addition to yield a hydrido-PtII carbene complex. 1H NMR studies on Watson-Crick base-pairs showed no significant effect of metallation. This journal is

Original languageEnglish
Pages (from-to)13365-13368
Number of pages4
JournalChemical Communications
Volume56
Issue number87
DOIs
Publication statusPublished - 11 Nov 2020

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