On the merge of fungal activity with ionic liquids towards the development of new biotechnological processes

M. Petkovic, J. Ferguson, A. Bohn, J. R. Trindade, I. Martins, C. Leitão, M. B. Carvalho, C. Rodrigues, H. Garcia, R. Ferreira, K. R. Seddon, L. P. N. Rebelo, C. Silva Pereira

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

In this work we present the toxicological assessment of sixteen ionic liquids (ILs), containing either an imidazolium, or a pyridinium ring, or a cholinium function, to filamentous fungi (Penicillium sp.) as eukaryotic model organisms. It is shown that among this family there are members which show much higher tolerance towards ILs than any other microorganism studied so far. Furthermore, guided by the paradigm that the choice of an ionic liquid as catalyst can alter the outcome of a given chemical reaction, we investigated the ability of ILs to alter the metabolic profile in fungi. The metabolic footprinting, using ESI-MS, revealed that fungal cultures respond to specific liquid salts by changing the cell biochemistry, resulting in a different pattern of secondary metabolites.

Original languageEnglish
Pages (from-to)197-207
Number of pages11
JournalACS Symposium Series
Volume1038
DOIs
Publication statusPublished - 28 Apr 2010
Event236th National Meeting and Exposition of the American Chemical Society, ACS 2008 - Philadelpia, PA, United States
Duration: 17 Aug 200821 Aug 2008

Keywords

  • Ionic liquids
  • Toxicity
  • Imidazolium ionic

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