Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus

Carolina Ferreira; Marta Leal; Mariana Andrade; Patrícia Abrantes; Miguel Viveiros; Sofia Santos Costa; Isabel Couto

Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus

Carolina Ferreira, Marta Leal, Mariana Andrade, Patrícia Abrantes, Miguel Viveiros, Sofia Santos Costa, Isabel Couto

Research output: Contribution to conference › Poster › peer-review

Abstract

Multidrug efflux pumps (MDR EPs) play a major role in the emergence of antimicrobial resistance (AMR), particularly multidrug resistance phenotypes. NorA is a main native MDR EP in Staphylococcus aureus. Its encoding gene is part of the S. aureus core genome, but less is known about
the occurrence of norA and other MDR EPs across the Staphylococcus genus. This study aims to analyze the presence of norA across staphylococci and identify other putative MDR EP determinants in seven pathogenic staphylococcal species.

Original language	English
Pages	17-17
Number of pages	1
Publication status	Published - 18 Nov 2024
Event	VII International Conference NOVAHealth: Tackling Pandemics: Strategies for Prevention, Preparedness and Response - Lisbon, Portugal Duration: 18 Nov 2024 → 18 Nov 2024

Conference

Conference	VII International Conference NOVAHealth: Tackling Pandemics
Country/Territory	Portugal
City	Lisbon
Period	18/11/24 → 18/11/24

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Cite this

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title = "Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus",

abstract = "Multidrug efflux pumps (MDR EPs) play a major role in the emergence of antimicrobial resistance (AMR), particularly multidrug resistance phenotypes. NorA is a main native MDR EP in Staphylococcus aureus. Its encoding gene is part of the S. aureus core genome, but less is known about the occurrence of norA and other MDR EPs across the Staphylococcus genus. This study aims to analyze the presence of norA across staphylococci and identify other putative MDR EP determinants in seven pathogenic staphylococcal species.",

author = "Carolina Ferreira and Marta Leal and Mariana Andrade and Patr{\'i}cia Abrantes and Miguel Viveiros and Costa, \{Sofia Santos\} and Isabel Couto",

note = "Funding: Project BIOSAFE (LISBOA-01-0145-FEDER-030713, PTDC/CAL-EST/30713/2017) funded by FEDER and by Funda{\c c}{\~a}o para a Ci{\^e}ncia e a Tecnologia (FCT, Portugal). Further support by FCT to GHTM (UID/04413/2020); LA-REAL (LA/P/0117/2020); DREBI project (2022.07931.PTDC); SSC (CEECINST/00042/2021/CP1773/CT0009) and PhD Grants 2021.05063.BD (CF), 2023.02437.BD (ML) and UI/BD/154472/2022 (MA).; VII International Conference NOVAHealth: Tackling Pandemics : Strategies for Prevention, Preparedness and Response ; Conference date: 18-11-2024 Through 18-11-2024",

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day = "18",

language = "English",

pages = "17--17",

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TY - CONF

T1 - Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus

AU - Ferreira, Carolina

AU - Leal, Marta

AU - Andrade, Mariana

AU - Abrantes, Patrícia

AU - Viveiros, Miguel

AU - Costa, Sofia Santos

AU - Couto, Isabel

N1 - Funding: Project BIOSAFE (LISBOA-01-0145-FEDER-030713, PTDC/CAL-EST/30713/2017) funded by FEDER and by Fundação para a Ciência e a Tecnologia (FCT, Portugal). Further support by FCT to GHTM (UID/04413/2020); LA-REAL (LA/P/0117/2020); DREBI project (2022.07931.PTDC); SSC (CEECINST/00042/2021/CP1773/CT0009) and PhD Grants 2021.05063.BD (CF), 2023.02437.BD (ML) and UI/BD/154472/2022 (MA).

PY - 2024/11/18

Y1 - 2024/11/18

N2 - Multidrug efflux pumps (MDR EPs) play a major role in the emergence of antimicrobial resistance (AMR), particularly multidrug resistance phenotypes. NorA is a main native MDR EP in Staphylococcus aureus. Its encoding gene is part of the S. aureus core genome, but less is known about the occurrence of norA and other MDR EPs across the Staphylococcus genus. This study aims to analyze the presence of norA across staphylococci and identify other putative MDR EP determinants in seven pathogenic staphylococcal species.

AB - Multidrug efflux pumps (MDR EPs) play a major role in the emergence of antimicrobial resistance (AMR), particularly multidrug resistance phenotypes. NorA is a main native MDR EP in Staphylococcus aureus. Its encoding gene is part of the S. aureus core genome, but less is known about the occurrence of norA and other MDR EPs across the Staphylococcus genus. This study aims to analyze the presence of norA across staphylococci and identify other putative MDR EP determinants in seven pathogenic staphylococcal species.

UR - https://www.unl.pt/wp-content/uploads/2024/09/Programme.pdf

M3 - Poster

SP - 17

EP - 17

T2 - VII International Conference NOVAHealth: Tackling Pandemics

Y2 - 18 November 2024 through 18 November 2024

ER -

Occurrence of norA and other multidrug efflux pump determinants across the Staphylococcus genus

Abstract

Conference

UN SDGs

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