TY - JOUR
T1 - Obsessive-compulsive disorder and executive deficits in two patients with primary dystonia
AU - Guimarães, João Manuel Ferreira
AU - Bugalho, Paulo Mourão Fialho
AU - Corrêa, João Bernardo Barahona Simões Regalo
AU - Xavier, Fernando Miguel Teixeira
PY - 2006/1/1
Y1 - 2006/1/1
N2 - In spite of the high prevalence of behavioral and cognitive disturbances found in most basal ganglia disorders and attributed to fronto-striatal dysfunction, the existence of psychiatric and cognitive symptoms in patients with primary dystonia remains controversial. We present a 42-year-old female with primary writer's cramp and obsessive-compulsive disorder (OCD) and a 59-year-old male with Meigs syndrome, idiopathic torticollis and OCD. Both patients had mild executive dysfunction. The coexistence of psychiatric, cognitive and motor symptoms of different intensity may be explained by variable dysfunction on different frontal-striatal loops, as proposed by the open interconnected model of fronto-striatal circuits.
AB - In spite of the high prevalence of behavioral and cognitive disturbances found in most basal ganglia disorders and attributed to fronto-striatal dysfunction, the existence of psychiatric and cognitive symptoms in patients with primary dystonia remains controversial. We present a 42-year-old female with primary writer's cramp and obsessive-compulsive disorder (OCD) and a 59-year-old male with Meigs syndrome, idiopathic torticollis and OCD. Both patients had mild executive dysfunction. The coexistence of psychiatric, cognitive and motor symptoms of different intensity may be explained by variable dysfunction on different frontal-striatal loops, as proposed by the open interconnected model of fronto-striatal circuits.
KW - BASAL GANGLIA
KW - fronto-striatal circuits
KW - CIRCUITS
KW - primary dystonia
KW - ORGANIZATION
KW - obsessive-compulsive disorder
KW - executive dysfunction
U2 - 10.1016/j.parkreldis.2005.12.009
DO - 10.1016/j.parkreldis.2005.12.009
M3 - Article
C2 - 16731024
VL - 12
SP - 388
EP - 391
JO - Parkinsonism & Related Disorders
JF - Parkinsonism & Related Disorders
SN - 1353-8020
IS - 6
ER -