Non-miotic improvement in binocular near vision with a topical compound formula for presbyopia correction

Felipe Vejarano, Jorge Alió, Rafael Iribarren, Carla Lança

Research output: Contribution to journalArticlepeer-review

4 Downloads (Pure)

Abstract

Introduction: The aim of this case series was to examine the association between unaided binocular visual acuity for near vision and pupil change after the instillation of a special topical formulation for presbyopia treatment. Methods: This was a case series consisting of consecutive participants with presbyopia aged 40–70 years who were tested for visual acuity and pupil diameter before and 2 h after instillation of a formulation of pilocarpine and phenylephrine drops (FOV Tears) for presbyopia. Participants underwent subjective refraction, photopic and scotopic pupil diameter measurement and unaided monocular and binocular visual acuity testing by logMAR for distance and near vision both pre- and post-instillation of eye drops. Results: The study enrolled 363 subjects (n = 176 women, 48%) with a mean (± standard deviation) age of 50.4 ± 5.8 years. Mean spherical equivalent (SE) changed significantly (− 0.17 Diopters) after instillation of the FOV Tears formulation (p < 0.001). Post-instillation of eye drops, the scotopic pupil diameter decreased by 0.97 ± 0.98 mm, and the near visual acuity by logMAR improved significantly by nearly two lines (p < 0.01). In the linear regression analyses, age (p < 0.001) and SE pre-drop instillation (p < 0.001) were associated with unaided binocular visual acuity. The changes in photopic pupil diameter and the scotopic pupil diameter were not associated with unaided binocular visual acuity. Conclusions: The use of the pilocarpine and phenylephrine formulation (FOV Tears) improved binocular visual acuity for near vision in presbyopic patients, and the effect was independent of pupil change.

Original languageEnglish
Pages (from-to)1013-1024
Number of pages12
JournalOphthalmology and Therapy
Volume12
Issue number2
DOIs
Publication statusPublished - Apr 2023

Keywords

  • Near visual acuity
  • Phenylephrine
  • Pilocarpine
  • Presbyopia
  • Pupil diameter

Fingerprint

Dive into the research topics of 'Non-miotic improvement in binocular near vision with a topical compound formula for presbyopia correction'. Together they form a unique fingerprint.

Cite this