Estudo arterial coronário não invasivo com tomografia computorizada por multidetectores

Translated title of the contribution: Non-invasive coronary artery evaluation with multidetector computed tomography

Miguel Mota Carmo, Teresa Ferreira, Jorge Quininha, José Ferreira

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Objectives: To evaluate the diagnostic accuracy of 16-slice multidetector spiral computed tomography in the non-invasive detection of coronary artery disease compared to invasive coronary angiography. Design: Prospective study. Patients: We studied 35 patients, 21 men and 14 women, mean age 63.6 ± 13.8 years, who underwent elective invasive coronary angiography one week prior to undergoing 16-slice multidetector computed tomography. Methods: We used a Toshiba Aquilion 16-slice system. Helical acquisition was performed with breath holding after injection of 140 ml of a contrast agent into a peripheral vein. Cross-sectional images were reconstructed with a slice thickness of 0.5 mm or 1 mm. We set 15 anatomical segments for the coronaiy tree and the evaluation was performed independently for both techniques. Coronary artery lesions with over 50% reduction in diameter were considered significant. Findings from both techniques were evaluated using ROC curve analysis. Results: It was possible to evaluate 87.7% of the coronary tree segments; heavy calcification, enability to perform breath holding, motion artefacts and stents made evaluation of the other segments impossible. Overall sensitivity and specificity were 85.9% and 98.2% respectively with a 95% confidence interval; positive predictive value was 87% and negative predictive value 97%. For the different anatomical segments, sensitivity and specificity segments, 88.9% and 97.8%; medial 90.9% and 95.8%; distal 86.7% and 99.1% respectively. Conclusions: Multidetector computed tomography is a promising non-invasive technique for detecting or ruling out significant coronary lesions.

Translated title of the contributionNon-invasive coronary artery evaluation with multidetector computed tomography
Original languagePortuguese
Pages (from-to)667-679
Number of pages13
JournalRevista Portuguesa de Cardiologia
Volume24
Issue number5
Publication statusPublished - 1 May 2005

Keywords

  • Coronary angiography
  • Coronary disease
  • Multidetector computed tomography

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