Non-enzymatic lab-on-paper devices for biosensing applications

Ana Carolina Marques, Tomás Pinheiro, Gabriela Vieira Martins, Ana Rita Cardoso, Rodrigo Martins, Maria Goreti Sales, Elvira Fortunato

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

12 Citations (Scopus)


Lab-on-paper devices constitute a promising tool for biosensing systems due to their easiness of fabrication and use, inherent low-cost, easy tailoring in terms of device architecture and/or function, biocompatibility and easy disposal. When combined with non-enzymatic approaches the increase on device's shelf life, stability and analytical features improvement can be achieved. In this chapter, a brief description of the lab-on-paper concept is presented alongside a review of works reporting non-enzymatic approaches on paper-based platforms using two of the most common transduction mechanisms: optical and electrochemical methods.

Original languageEnglish
Title of host publicationPaper Based Sensors
EditorsArben Merkoçi
PublisherElsevier B.V.
Number of pages49
Publication statusPublished - 2020

Publication series

NameComprehensive Analytical Chemistry
PublisherElsevier B.V.
ISSN (Print)0166-526X


  • Biomimetic materials
  • Biosensors
  • Lab-on-paper
  • Nanoparticles
  • Non-enzymatic
  • Paper-based


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