NMR Techniques for the Study of Transient Intermolecular Interactions

Jesús Angulo; Ana Ardá; Eurico J. Cabrita; Manuel Martín-Pastor; Jesús Jiménez-Barbero; Pedro M. Nieto

doi:10.1002/9783527664610.ch9

NMR Techniques for the Study of Transient Intermolecular Interactions

Jesús Angulo, Ana Ardá, Eurico J. Cabrita, Manuel Martín-Pastor, Jesús Jiménez-Barbero, Pedro M. Nieto

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Citations (Scopus)

Abstract

NMR is one of the most versatile techniques for the analysis of molecular interactions. In this review we cover the main techniques and applications of the ligand-observed methods: transfer-NOESY, Saturation Transfer Difference NMR and Diffusion NMR. They have in common that monitoring the signals of the small molecule, used in high excess, allowed to obtain information about the ligand within the transient complex.

Original language	English
Title of host publication	Structure Elucidation in Organic Chemistry
Subtitle of host publication	The Search for the Right Tools
Publisher	Wiley-Blackwell
Pages	325-360
Number of pages	36
ISBN (Electronic)	9783527664610
ISBN (Print)	9783527333363
DOIs	https://doi.org/10.1002/9783527664610.ch9
Publication status	Published - 27 Apr 2015

Keywords

Diffusion
Epitope mapping
Ligand-observed Techniques
NMR
STD-NMR
Transfer-NOE
Transient complexes

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10.1002/9783527664610.ch9

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AU - Ardá, Ana

AU - Cabrita, Eurico J.

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AU - Jiménez-Barbero, Jesús

AU - Nieto, Pedro M.

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KW - Epitope mapping

KW - Ligand-observed Techniques

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KW - STD-NMR

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NMR Techniques for the Study of Transient Intermolecular Interactions

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Keywords

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