Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence

Jean Bousquet, Holger J. Schünemann, Akdis Togias, Claus Bachert, Martina Erhola, Peter W. Hellings, Ludger Klimek, Oliver Pfaar, Dana Wallace, Ignacio Ansotegui, Ioana Agache, Anna Bedbrook, Karl Christian Bergmann, Mike Bewick, Philippe Bonniaud, Sinthia Bosnic-Anticevich, Isabelle Bossé, Jacques Bouchard, Louis Philippe Boulet, Jan Brozek & 30 others Guy Brusselle, Moises A. Calderon, Walter G. Canonica, Luis Caraballo, Vicky Cardona, Thomas Casale, Lorenzo Cecchi, Derek K. Chu, Elisio M. Costa, Alvaro A. Cruz, Wienczyslawa Czarlewski, Gennaro D'Amato, Philippe Devillier, Mark Dykewicz, Motohiro Ebisawa, Jean Louis Fauquert, Wytske J. Fokkens, Joao A. Fonseca, Jean François Fontaine, Bilun Gemicioglu, Roy Gerth van Wijk, Tari Haahtela, Susanne Halken, Despo Ierodiakonou, Tomohisa Iinuma, Juan Carlos Ivancevich, Marek Jutel, Igor Kaidashev, Pedro Carreiro-Martins, Maria Teresa Ventura

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.

Original languageEnglish
JournalJournal Of Allergy And Clinical Immunology
DOIs
Publication statusPublished - 2019

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Asthma
Guidelines
Therapeutics
Allergens
Patient Selection
Randomized Controlled Trials
Allergic Rhinitis
Technology
Drug Therapy

Keywords

  • Allergic rhinitis
  • Allergic Rhinitis and Its Impact on Asthma
  • Development and Evaluation
  • Grading of Recommendations Assessment
  • guidelines
  • real-world evidence

Cite this

Bousquet, Jean ; Schünemann, Holger J. ; Togias, Akdis ; Bachert, Claus ; Erhola, Martina ; Hellings, Peter W. ; Klimek, Ludger ; Pfaar, Oliver ; Wallace, Dana ; Ansotegui, Ignacio ; Agache, Ioana ; Bedbrook, Anna ; Bergmann, Karl Christian ; Bewick, Mike ; Bonniaud, Philippe ; Bosnic-Anticevich, Sinthia ; Bossé, Isabelle ; Bouchard, Jacques ; Boulet, Louis Philippe ; Brozek, Jan ; Brusselle, Guy ; Calderon, Moises A. ; Canonica, Walter G. ; Caraballo, Luis ; Cardona, Vicky ; Casale, Thomas ; Cecchi, Lorenzo ; Chu, Derek K. ; Costa, Elisio M. ; Cruz, Alvaro A. ; Czarlewski, Wienczyslawa ; D'Amato, Gennaro ; Devillier, Philippe ; Dykewicz, Mark ; Ebisawa, Motohiro ; Fauquert, Jean Louis ; Fokkens, Wytske J. ; Fonseca, Joao A. ; Fontaine, Jean François ; Gemicioglu, Bilun ; van Wijk, Roy Gerth ; Haahtela, Tari ; Halken, Susanne ; Ierodiakonou, Despo ; Iinuma, Tomohisa ; Ivancevich, Juan Carlos ; Jutel, Marek ; Kaidashev, Igor ; Carreiro-Martins, Pedro ; Ventura, Maria Teresa. / Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. In: Journal Of Allergy And Clinical Immunology. 2019.
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title = "Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence",
abstract = "The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.",
keywords = "Allergic rhinitis, Allergic Rhinitis and Its Impact on Asthma, Development and Evaluation, Grading of Recommendations Assessment, guidelines, real-world evidence",
author = "Jean Bousquet and Sch{\"u}nemann, {Holger J.} and Akdis Togias and Claus Bachert and Martina Erhola and Hellings, {Peter W.} and Ludger Klimek and Oliver Pfaar and Dana Wallace and Ignacio Ansotegui and Ioana Agache and Anna Bedbrook and Bergmann, {Karl Christian} and Mike Bewick and Philippe Bonniaud and Sinthia Bosnic-Anticevich and Isabelle Boss{\'e} and Jacques Bouchard and Boulet, {Louis Philippe} and Jan Brozek and Guy Brusselle and Calderon, {Moises A.} and Canonica, {Walter G.} and Luis Caraballo and Vicky Cardona and Thomas Casale and Lorenzo Cecchi and Chu, {Derek K.} and Costa, {Elisio M.} and Cruz, {Alvaro A.} and Wienczyslawa Czarlewski and Gennaro D'Amato and Philippe Devillier and Mark Dykewicz and Motohiro Ebisawa and Fauquert, {Jean Louis} and Fokkens, {Wytske J.} and Fonseca, {Joao A.} and Fontaine, {Jean Fran{\cc}ois} and Bilun Gemicioglu and {van Wijk}, {Roy Gerth} and Tari Haahtela and Susanne Halken and Despo Ierodiakonou and Tomohisa Iinuma and Ivancevich, {Juan Carlos} and Marek Jutel and Igor Kaidashev and Pedro Carreiro-Martins and Ventura, {Maria Teresa}",
year = "2019",
doi = "10.1016/j.jaci.2019.06.049",
language = "English",
journal = "Journal Of Allergy And Clinical Immunology",
issn = "0091-6749",
publisher = "MOSBY-ELSEVIER",

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Bousquet, J, Schünemann, HJ, Togias, A, Bachert, C, Erhola, M, Hellings, PW, Klimek, L, Pfaar, O, Wallace, D, Ansotegui, I, Agache, I, Bedbrook, A, Bergmann, KC, Bewick, M, Bonniaud, P, Bosnic-Anticevich, S, Bossé, I, Bouchard, J, Boulet, LP, Brozek, J, Brusselle, G, Calderon, MA, Canonica, WG, Caraballo, L, Cardona, V, Casale, T, Cecchi, L, Chu, DK, Costa, EM, Cruz, AA, Czarlewski, W, D'Amato, G, Devillier, P, Dykewicz, M, Ebisawa, M, Fauquert, JL, Fokkens, WJ, Fonseca, JA, Fontaine, JF, Gemicioglu, B, van Wijk, RG, Haahtela, T, Halken, S, Ierodiakonou, D, Iinuma, T, Ivancevich, JC, Jutel, M, Kaidashev, I, Carreiro-Martins, P & Ventura, MT 2019, 'Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence', Journal Of Allergy And Clinical Immunology. https://doi.org/10.1016/j.jaci.2019.06.049

Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence. / Bousquet, Jean; Schünemann, Holger J.; Togias, Akdis; Bachert, Claus; Erhola, Martina; Hellings, Peter W.; Klimek, Ludger; Pfaar, Oliver; Wallace, Dana; Ansotegui, Ignacio; Agache, Ioana; Bedbrook, Anna; Bergmann, Karl Christian; Bewick, Mike; Bonniaud, Philippe; Bosnic-Anticevich, Sinthia; Bossé, Isabelle; Bouchard, Jacques; Boulet, Louis Philippe; Brozek, Jan; Brusselle, Guy; Calderon, Moises A.; Canonica, Walter G.; Caraballo, Luis; Cardona, Vicky; Casale, Thomas; Cecchi, Lorenzo; Chu, Derek K.; Costa, Elisio M.; Cruz, Alvaro A.; Czarlewski, Wienczyslawa; D'Amato, Gennaro; Devillier, Philippe; Dykewicz, Mark; Ebisawa, Motohiro; Fauquert, Jean Louis; Fokkens, Wytske J.; Fonseca, Joao A.; Fontaine, Jean François; Gemicioglu, Bilun; van Wijk, Roy Gerth; Haahtela, Tari; Halken, Susanne; Ierodiakonou, Despo; Iinuma, Tomohisa; Ivancevich, Juan Carlos; Jutel, Marek; Kaidashev, Igor; Carreiro-Martins, Pedro; Ventura, Maria Teresa.

In: Journal Of Allergy And Clinical Immunology, 2019.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence

AU - Bousquet, Jean

AU - Schünemann, Holger J.

AU - Togias, Akdis

AU - Bachert, Claus

AU - Erhola, Martina

AU - Hellings, Peter W.

AU - Klimek, Ludger

AU - Pfaar, Oliver

AU - Wallace, Dana

AU - Ansotegui, Ignacio

AU - Agache, Ioana

AU - Bedbrook, Anna

AU - Bergmann, Karl Christian

AU - Bewick, Mike

AU - Bonniaud, Philippe

AU - Bosnic-Anticevich, Sinthia

AU - Bossé, Isabelle

AU - Bouchard, Jacques

AU - Boulet, Louis Philippe

AU - Brozek, Jan

AU - Brusselle, Guy

AU - Calderon, Moises A.

AU - Canonica, Walter G.

AU - Caraballo, Luis

AU - Cardona, Vicky

AU - Casale, Thomas

AU - Cecchi, Lorenzo

AU - Chu, Derek K.

AU - Costa, Elisio M.

AU - Cruz, Alvaro A.

AU - Czarlewski, Wienczyslawa

AU - D'Amato, Gennaro

AU - Devillier, Philippe

AU - Dykewicz, Mark

AU - Ebisawa, Motohiro

AU - Fauquert, Jean Louis

AU - Fokkens, Wytske J.

AU - Fonseca, Joao A.

AU - Fontaine, Jean François

AU - Gemicioglu, Bilun

AU - van Wijk, Roy Gerth

AU - Haahtela, Tari

AU - Halken, Susanne

AU - Ierodiakonou, Despo

AU - Iinuma, Tomohisa

AU - Ivancevich, Juan Carlos

AU - Jutel, Marek

AU - Kaidashev, Igor

AU - Carreiro-Martins, Pedro

AU - Ventura, Maria Teresa

PY - 2019

Y1 - 2019

N2 - The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.

AB - The selection of pharmacotherapy for patients with allergic rhinitis aims to control the disease and depends on many factors. Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines have considerably improved the treatment of allergic rhinitis. However, there is an increasing trend toward use of real-world evidence to inform clinical practice, especially because randomized controlled trials are often limited with regard to the applicability of results. The Contre les Maladies Chroniques pour un Vieillissement Actif (MACVIA) algorithm has proposed an allergic rhinitis treatment by a consensus group. This simple algorithm can be used to step up or step down allergic rhinitis treatment. Next-generation guidelines for the pharmacologic treatment of allergic rhinitis were developed by using existing GRADE-based guidelines for the disease, real-world evidence provided by mobile technology, and additive studies (allergen chamber studies) to refine the MACVIA algorithm.

KW - Allergic rhinitis

KW - Allergic Rhinitis and Its Impact on Asthma

KW - Development and Evaluation

KW - Grading of Recommendations Assessment

KW - guidelines

KW - real-world evidence

UR - http://www.scopus.com/inward/record.url?scp=85073509724&partnerID=8YFLogxK

U2 - 10.1016/j.jaci.2019.06.049

DO - 10.1016/j.jaci.2019.06.049

M3 - Review article

JO - Journal Of Allergy And Clinical Immunology

JF - Journal Of Allergy And Clinical Immunology

SN - 0091-6749

ER -