New Synthesis of Gold- and Silver-Based Nano-Tetracycline Composites

Jamila Djafari, Catarina Marinho, Tiago Santos, Gilberto Igrejas, Carmen Torres, José Luis Capelo, Patricia Poeta, Carlos Lodeiro, Javier Fernández-Lodeiro

Research output: Contribution to journalArticle

10 Citations (Scopus)
4 Downloads (Pure)


A new synthetic methodology of water-soluble gold and silver nanoparticles (AuNPs@TC and AgNPs@TC), using the antibiotic tetracycline (TC) as co-reducing and stabilizing agent, is reported. Both colloids exhibit high water stability. The average sizes obtained were 25±10 and 15±5 nm, respectively. Both composites were tested against TC-resistant bacteria, presenting an increasing antibacterial effect in the case of AgNPs@TC. The sensing towards metal ions was also explored. An interesting and reversible affinity of AuNPs@TC towards AlIII cations in an aqueous system was also observed.

Original languageEnglish
Pages (from-to)206-212
Number of pages7
Issue number3
Publication statusPublished - 1 Jun 2016


  • aluminum detection
  • antimicrobial studies
  • gold and silver nanoparticles
  • nanoantibiotics
  • nanochemical sensor

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