@article{95a419804e2e49359738a8f06493e510,
title = "New Synthesis of Gold- and Silver-Based Nano-Tetracycline Composites",
abstract = "A new synthetic methodology of water-soluble gold and silver nanoparticles (AuNPs@TC and AgNPs@TC), using the antibiotic tetracycline (TC) as co-reducing and stabilizing agent, is reported. Both colloids exhibit high water stability. The average sizes obtained were 25±10 and 15±5 nm, respectively. Both composites were tested against TC-resistant bacteria, presenting an increasing antibacterial effect in the case of AgNPs@TC. The sensing towards metal ions was also explored. An interesting and reversible affinity of AuNPs@TC towards AlIII cations in an aqueous system was also observed.",
keywords = "aluminum detection, antimicrobial studies, gold and silver nanoparticles, nanoantibiotics, nanochemical sensor",
author = "Jamila Djafari and Catarina Marinho and Tiago Santos and Gilberto Igrejas and Carmen Torres and Capelo, {Jos{\'e} Luis} and Patricia Poeta and Carlos Lodeiro and Javier Fern{\'a}ndez-Lodeiro",
note = "J.D., C.L,. and J.F.-L. conceived and designed the experiments; J.D. and J.F.-L. performed the synthesis and characterization of the TC functionalized Ag and Au NPs, as well as the metal-ion sensing studies. C.M., T.S., G.I., and P.P. studied the bacterial interactions with the NPs. C.T. provided the TC bacterial resistant strains. All authors have analyzed the data. J.F.L., J.D., C.L, J.L.-C., C.M., P.P., and G.I. wrote and corrected the paper. C.L., J.L.-C., G.I., and P.P. contributed with reagents/materials/analysis tools. J.F.-L. thanks Fundacao para a Ciencia e a Tecnologia-Ministerio de Ciencia e Educacao (FCT/MEC) (Portugal) for his postdoctoral grant reference SFRH/BPD/93982/2013. J.D. thanks Proteomass Scientific Society for a PhD research grant. This work was supported by the Associate Laboratory for Green Chemistry LAQV, which is financed by national funds from FCT/MEC (UID/QUI/50006/2013) and co-financed by the European Regional Development Fund (ERDF) under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007265) and by the Unidade de Ciencias Biomoleculares Aplicadas-UCIBIO, which is financed by national funds from FCT/MEC (UID/Multi/04378/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007728). All authors thank the Proteomass Scientific Society, General Funds (Portugal) for financial support.",
year = "2016",
month = jun,
day = "1",
doi = "10.1002/open.201600016",
language = "English",
volume = "5",
pages = "206--212",
journal = "ChemistryOpen",
issn = "2191-1363",
publisher = "Wiley-VCH Verlag | Wiley Open Access",
number = "3",
}