New organocatalysts derived from tartaric and glyceric acids for direct aldol reactions

Research output: Contribution to journalArticle

15 Citations (Scopus)


The synthesis of several new pyrrolidine based asymmetric organocatalysts derived from tartaric, glyceric acids and a pyrrolidine moiety is described with a study of their application in the development of an enantioselective aldol protocol. The influence of different proton donor groups, such as a primary hydroxyl or a carboxylic acid group, or their absence, on the efficiency of the organocatalyst was studied. The configuration of the tartrate derived catalysts and the presence of the rigid butane-2,3-diacetal were found to have a strong influence on the stereoselective outcome of the aldol reaction
Original languageUnknown
Pages (from-to)1262-1271
Issue number17
Publication statusPublished - 1 Jan 2012

Cite this