New insights into the population structure of Anopheles gambiae s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.

Patrícia Salgueiro, Marta Moreno, Frederic Simard, David O'Brochta, João Pedro Soares da Silva Pinto

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Transposable elements (TEs) are mobile portions of DNA that are able to replicate and spread in the genome of many organisms. TEs can be used as a means to insert transgenes in insects, being stably inherited throughout generations. Anopheles gambiae is the main vector of human malaria in Sub-Saharan Africa. Given the extraordinary burden this disease imposes, the mosquito became a choice target for genetic control approaches with the purpose of reducing malaria transmission. In this study, we investigated the abundance and distribution of Herves TE in An. gambiae s.s. from Cameroon and four islands in the Gulf of Guinea, in order to determine their genetic structure. We have detected a population subdivision between Equatorial Guinea islands and the islands of São Tomé, Príncipe and mainland. This partitioning associates more with political rather than geographic boundaries, possibly reflecting different mainland source populations colonizing the islands.
Original languageEnglish
Article numbere62964
JournalPLoS ONE
Volume8
Issue number4
DOIs
Publication statusPublished - 1 Jan 2013

UN Sustainable Development Goals (SDGs)

  • SDG 3 - Good Health and Well-Being

Fingerprint Dive into the research topics of 'New insights into the population structure of <em>Anopheles gambiae</em> s.s. in the Gulf of Guinea islands revealed by Herves transposable elements.'. Together they form a unique fingerprint.

Cite this