Nanotechnology-Ocular Devices for Glaucoma Treatment: A Literature Review

Joana Cardigos, Quirina Ferreira, Sara Crisóstomo, Nuno Moura-Coelho, João Paulo Cunha, Luís Abegão Pinto, Joana Tavares Ferreira

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Nanotechnology enabled the development of materials and devices with great utility in different fields of medicine. By using engineered-based nano-devices and structures, human biological systems may be controlled and repaired at a molecular scale, ultimately leading to a biological benefit. In particular, in the field of glaucoma treatment, nanotechnology may, for example, enhance drug residence time on the ocular surface and ocular bioavailability, as well as improve surgical success by both optimizing postoperative scarring and providing a wider safety window. Further studies are still needed to entirely explain the pharmacodynamics of nanotechnology-based therapeutic approaches and prove their biological consequences in human eyes. This review aims to summarize the literature concerning the advances in nanotechnology, specifically regarding ocular devices applied to the treatment of glaucoma.

Original languageEnglish
Pages (from-to)111-117
Number of pages7
JournalCurrent eye research
Volume44
Issue number2
Early online date12 Oct 2018
DOIs
Publication statusPublished - 21 Feb 2019

Keywords

  • Glaucoma
  • nano-devices
  • nanomaterials
  • nanotechnology
  • ocular devices

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