Electron transfer and dissociative electron attachment to 3-methyluracil (3meU) and 1-methylthymine (1meT) yielding anion formation have been investigated in atom-molecule collision and electron attachment experiments, respectively. The former has been studied in the collision energy range 14-100 eV whereas the latter in the 0-15 eV incident electron energy range. In the present studies, emphasis is given to the reaction channel resulting in the loss of the methyl group from the N-sites with the extra charge located on the pyrimidine ring. This particular reaction channel has neither been approached in the context of dissociative electron attachment nor in atom-molecule collisions yet. Quantum chemical calculations have been performed in order to provide some insight into the dissociation mechanism involved along the N-CH3 bond reaction coordinate. The calculations provide support to the threshold value derived from the electron transfer measurements, allowing for a better understanding of the role of the potassium cation as a stabilising agent in the collision complex. The present comparative study gives insight into the dynamics of the decaying transient anion and more precisely into the competition between dissociation and auto-detachment.
- NEGATIVE-ION FORMATION
- ATOM-MOLECULE COLLISIONS
- DNA BASES
Almeida, D., Kinzel, D., Silva, F. F. D., Puschnigg, B., Gschliesser, D., Scheier, P., ... González, L. (2013). N-site de-methylation in pyrimidine bases as studied by low energy electrons and ab initio calculations. Physical Chemistry Chemical Physics, 15(27), 11431-11440. https://doi.org/10.1039/c3cp50548k