Multiple source phototherapy in breast cancer: A viability study

A. Lopes, A. Gabriel, J. Machado, P. Ribeiro, R. Gomes, Jõao M P Coelho, C. O. Silva, C. P. Reis, José Paulo Santos, Pedro Manuel Cardoso Vieira

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Radiation therapy is one of many common treatments applied to breast cancer. Most usual radiation sources applied are ionizing radiation, such as g-rays and X-rays, and non-ionizing radiation such as ultraviolet radiation. The possibility of using near infrared light to photoactivate a drug inside an 8 cm diameter biological object is discussed in this work via Monte Carlo simulations. Two simulation setups performed in the Geant4/GAMOS framework are presented in order to study the viability of photoactivating a drug by using several near infrared light sources. The overall objective of this technique is to minimize energy concentrated at objects surface and maximize it in a predefined region of interest. Results show an increase energy absorption in the desired region of interest inside a 8 cm object, when a higher absorption particle is present. With the use of multiple sources it is possible to photoactivate the drug while causing minimal damage to the surface of the radiated object.

Original languageEnglish
Title of host publicationBIODEVICES 2016 - 9th International Conference on Biomedical Electronics and Devices, Proceedings; Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016
PublisherSciTePress
Pages247-250
Number of pages4
ISBN (Electronic)978-989758170-0
Publication statusPublished - 2016
Event9th International Conference on Biomedical Electronics and Devices, BIODEVICES 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016 - Rome, Italy
Duration: 21 Feb 201623 Feb 2016

Conference

Conference9th International Conference on Biomedical Electronics and Devices, BIODEVICES 2016 - Part of 9th International Joint Conference on Biomedical Engineering Systems and Technologies, BIOSTEC 2016
CountryItaly
CityRome
Period21/02/1623/02/16

Keywords

  • Breast cancer
  • GAMOS
  • Monte carlo
  • Near infrared
  • Phototerapy
  • Spectroscopy

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