TY - JOUR
T1 - MRSA causing infections in hospitals in Greater Metropolitan New York
T2 - Major shift in the dominant clonal type between 1996 and 2014
AU - Pardos De La Gandara, Maria
AU - Curry, Marie
AU - Berger, Judith
AU - Burstein, David
AU - Della-Latta, Phyllis
AU - Kopetz, Virgina
AU - Quale, John
AU - Spitzer, Eric
AU - Tan, Rexie
AU - Urban, Carl
AU - Wang, Guiqing
AU - Whittier, Susan
AU - De Lencastre, Herminia
AU - Tomasz, Alexander
PY - 2016/6/1
Y1 - 2016/6/1
N2 - A surveillance study in 1996 identified the USA100 clone (ST5/SCCmecII)-also known as the "New York/Japan" clone - as the most prevalent MRSA causing infections in 12 New York City hospitals. Here we update the epidemiology of MRSA in seven of the same hospitals eighteen years later in 2013/14. Most of the current MRSA isolates (78 of 121) belonged to the MRSA clone USA300 (CC8/SCCmecIV) but the USA100 clone-dominant in the 1996 survey-still remained the second most frequent MRSA (25 of the 121 isolates) causing 32% of blood stream infections. The USA300 clone was most common in skin and soft tissue infections (SSTIs) and was associated with 84.5% of SSTIs compared to 5% caused by the USA100 clone. Our data indicate that by 2013/14, the USA300 clone replaced the New York/Japan clone as the most frequent cause of MRSA infections in hospitals in Metropolitan New York. In parallel with this shift in the clonal type of MRSA, there was also a striking change in the types of MRSA infections from 1996 to 2014.
AB - A surveillance study in 1996 identified the USA100 clone (ST5/SCCmecII)-also known as the "New York/Japan" clone - as the most prevalent MRSA causing infections in 12 New York City hospitals. Here we update the epidemiology of MRSA in seven of the same hospitals eighteen years later in 2013/14. Most of the current MRSA isolates (78 of 121) belonged to the MRSA clone USA300 (CC8/SCCmecIV) but the USA100 clone-dominant in the 1996 survey-still remained the second most frequent MRSA (25 of the 121 isolates) causing 32% of blood stream infections. The USA300 clone was most common in skin and soft tissue infections (SSTIs) and was associated with 84.5% of SSTIs compared to 5% caused by the USA100 clone. Our data indicate that by 2013/14, the USA300 clone replaced the New York/Japan clone as the most frequent cause of MRSA infections in hospitals in Metropolitan New York. In parallel with this shift in the clonal type of MRSA, there was also a striking change in the types of MRSA infections from 1996 to 2014.
UR - http://www.scopus.com/inward/record.url?scp=84974845979&partnerID=8YFLogxK
U2 - 10.1371/journal.pone.0156924
DO - 10.1371/journal.pone.0156924
M3 - Article
AN - SCOPUS:84974845979
SN - 1932-6203
VL - 11
JO - PLoS ONE
JF - PLoS ONE
IS - 6
M1 - e0156924
ER -