Globalization of manufacturing and the enlargement of production networks bear the problem of logistics. These worldwide non-hierarchical manufacturing and distributing networks are characterized by non-centralized decision making, thus increasing the autonomy of the hub organizations and enabling different rules and procedures for decision making within the same supply chain, but decreasing the effectiveness in terms of integration, interoperability, and transportation. The major cause for that is due to different systems and information structures. This paper suggests aligning the different enterprises operating within the network, using morphisms to relate and develop transformations between their information models and a common data exchange standard. Also, in order to manage the dynamism of internal information systems, a multi-Agent framework is proposed to detect changes, being capable of reacting to sustain the interoperability-enabling morphisms.