Molecular Weight Determination by Luminescent Chemo–enzymatics

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

A novel methodology for the determination of the number-average molecular weight (Mw) of linear, branched and crosslinked polymers is disclosed. The method relies on chemo-enzymatic-triggered fluorescence of dormant CdTe polymer-caged quantum dots synthesised in supercritical carbon dioxide. Polyurea (PURE) dendrimers (G1, G4, G5 and G6) are presented as a case study using the enzyme urease but the protocol is applicable to other synthetic and natural polymers. Simple, versatile and accurate, luminescent chemo-enzymatics is a low cost alternative to conventional techniques (e. g. GPC/SEC, MALDI-TOF).

Original languageEnglish
Pages (from-to)6818-6822
Number of pages5
JournalChemistrySelect
Volume1
Issue number21
DOIs
Publication statusPublished - 2016

Fingerprint

Polymers
Molecular weight
Natural polymers
Dendrimers
Urease
Carbon Dioxide
Semiconductor quantum dots
Fluorescence
Enzymes
Costs
polyurea

Keywords

  • chemo-enzymatic
  • dendrimers
  • molecular weight
  • polymer quantum dots
  • supercritical carbon dioxide

Cite this

@article{8d5502d04f10457ab507c29a5e10c664,
title = "Molecular Weight Determination by Luminescent Chemo–enzymatics",
abstract = "A novel methodology for the determination of the number-average molecular weight (Mw) of linear, branched and crosslinked polymers is disclosed. The method relies on chemo-enzymatic-triggered fluorescence of dormant CdTe polymer-caged quantum dots synthesised in supercritical carbon dioxide. Polyurea (PURE) dendrimers (G1, G4, G5 and G6) are presented as a case study using the enzyme urease but the protocol is applicable to other synthetic and natural polymers. Simple, versatile and accurate, luminescent chemo-enzymatics is a low cost alternative to conventional techniques (e. g. GPC/SEC, MALDI-TOF).",
keywords = "chemo-enzymatic, dendrimers, molecular weight, polymer quantum dots, supercritical carbon dioxide",
author = "Pires, {Rita F.} and Artur Moro and Anita Louren{\cc}o and Lima, {Jo{\~a}o C.} and Teresa Casimiro and Bonif{\'a}cio, {Vasco D.B.}",
note = "We acknowledge financial support from Fundacao para a Ciencia e a Tecnologia (FC&T, Lisbon, Portugal) through projects PTDC/CTM/099452/2008, PTDC/QEQ-PRS/2757/2012, grants SFRH/BD/109006/2015 (R.F.P.), SFRH/BPD/69210/2010 (A.M.) and IF Investigator position and project IF/00915/2014 (T.C.). The MIT-Portugal Program is also acknowledged.",
year = "2016",
doi = "10.1002/slct.201601301",
language = "English",
volume = "1",
pages = "6818--6822",
journal = "ChemistrySelect",
issn = "2365-6549",
publisher = "Wiley",
number = "21",

}

Molecular Weight Determination by Luminescent Chemo–enzymatics. / Pires, Rita F.; Moro, Artur; Lourenço, Anita; Lima, João C.; Casimiro, Teresa; Bonifácio, Vasco D.B.

In: ChemistrySelect, Vol. 1, No. 21, 2016, p. 6818-6822.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Molecular Weight Determination by Luminescent Chemo–enzymatics

AU - Pires, Rita F.

AU - Moro, Artur

AU - Lourenço, Anita

AU - Lima, João C.

AU - Casimiro, Teresa

AU - Bonifácio, Vasco D.B.

N1 - We acknowledge financial support from Fundacao para a Ciencia e a Tecnologia (FC&T, Lisbon, Portugal) through projects PTDC/CTM/099452/2008, PTDC/QEQ-PRS/2757/2012, grants SFRH/BD/109006/2015 (R.F.P.), SFRH/BPD/69210/2010 (A.M.) and IF Investigator position and project IF/00915/2014 (T.C.). The MIT-Portugal Program is also acknowledged.

PY - 2016

Y1 - 2016

N2 - A novel methodology for the determination of the number-average molecular weight (Mw) of linear, branched and crosslinked polymers is disclosed. The method relies on chemo-enzymatic-triggered fluorescence of dormant CdTe polymer-caged quantum dots synthesised in supercritical carbon dioxide. Polyurea (PURE) dendrimers (G1, G4, G5 and G6) are presented as a case study using the enzyme urease but the protocol is applicable to other synthetic and natural polymers. Simple, versatile and accurate, luminescent chemo-enzymatics is a low cost alternative to conventional techniques (e. g. GPC/SEC, MALDI-TOF).

AB - A novel methodology for the determination of the number-average molecular weight (Mw) of linear, branched and crosslinked polymers is disclosed. The method relies on chemo-enzymatic-triggered fluorescence of dormant CdTe polymer-caged quantum dots synthesised in supercritical carbon dioxide. Polyurea (PURE) dendrimers (G1, G4, G5 and G6) are presented as a case study using the enzyme urease but the protocol is applicable to other synthetic and natural polymers. Simple, versatile and accurate, luminescent chemo-enzymatics is a low cost alternative to conventional techniques (e. g. GPC/SEC, MALDI-TOF).

KW - chemo-enzymatic

KW - dendrimers

KW - molecular weight

KW - polymer quantum dots

KW - supercritical carbon dioxide

UR - http://www.scopus.com/inward/record.url?scp=85041897625&partnerID=8YFLogxK

U2 - 10.1002/slct.201601301

DO - 10.1002/slct.201601301

M3 - Article

VL - 1

SP - 6818

EP - 6822

JO - ChemistrySelect

JF - ChemistrySelect

SN - 2365-6549

IS - 21

ER -