TY - JOUR
T1 - Molecular characterization of methicillin-resistant Staphylococcus epidermidis clones: Evidence of geographic dissemination
AU - Miragaia, Maria
AU - Couto, Isabel
AU - Pereira, Sandro F.F.
AU - Kristinsson, Karl Gustaf
AU - Westh, Henrik T.
AU - Jarløv, Jens Otto
AU - Almeida, Jonas
AU - Santos Sanches, Ilda
AU - de Lencastre, H.
PY - 2002/1/1
Y1 - 2002/1/1
N2 - Denmark and Iceland are countries where the frequency ofmethicillin-resistantStaphylococcusaureus is very low due to strict infection control and restrictive antibiotic use policies. In contrast,methicillin-resistantS.epidermidis(MRSE) continues to be isolated as a nosocomial pathogen. Themoleculartyping by pulsed-field gel electrophoresis (PFGE) of 136MRSEisolates from five hospitals in Denmark and 94MRSEisolates from one hospital in Iceland collected in 1997 and 1998 defined 40 different patterns. Closely related PFGE types were found in isolates recovered in Iceland, Denmark, Mexico, Uruguay, Greece, and Cape Verde, evidencing for the first time thegeographicclonaldisseminationofMRSEstrains. The large majority (87.4%) of theMRSEisolates studied were multiresistant.
AB - Denmark and Iceland are countries where the frequency ofmethicillin-resistantStaphylococcusaureus is very low due to strict infection control and restrictive antibiotic use policies. In contrast,methicillin-resistantS.epidermidis(MRSE) continues to be isolated as a nosocomial pathogen. Themoleculartyping by pulsed-field gel electrophoresis (PFGE) of 136MRSEisolates from five hospitals in Denmark and 94MRSEisolates from one hospital in Iceland collected in 1997 and 1998 defined 40 different patterns. Closely related PFGE types were found in isolates recovered in Iceland, Denmark, Mexico, Uruguay, Greece, and Cape Verde, evidencing for the first time thegeographicclonaldisseminationofMRSEstrains. The large majority (87.4%) of theMRSEisolates studied were multiresistant.
KW - epidemiology
KW - hospitals
KW - coagulase-negative staphylococci
KW - catheter-related infections
KW - field gel-electrophoresis
KW - intensive-care unit
KW - strains
KW - aureus
KW - vancomycin
KW - susceptibility
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-0036161943&origin=inward&txGid=3fad1a93cca51a3d3faecb577aaff359
U2 - 10.1128/JCM.40.2.430-438.2002
DO - 10.1128/JCM.40.2.430-438.2002
M3 - Article
SN - 0095-1137
VL - 40
SP - 430
EP - 438
JO - Journal Of Clinical Microbiology
JF - Journal Of Clinical Microbiology
IS - 2
ER -