MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson's disease

Marta Esteves; Ricardo Abreu; Hugo Fernandes; Catarina Serra-Almeida; Patricia A. T. Martins; Marta Barao; Ana Clara Cristovao; Claudia Saraiva; Raquel Ferreira; Lino Ferreira; Liliana Bernardino

doi:10.1016/j.ymthe.2022.06.003

MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson's disease

Marta Esteves, Ricardo Abreu, Hugo Fernandes, Catarina Serra-Almeida, Patricia A. T. Martins, Marta Barao, Ana Clara Cristovao, Claudia Saraiva, Raquel Ferreira, Lino Ferreira, Liliana Bernardino

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Original language	English
Pages (from-to)	3176-3192
Journal	Molecular Therapy
Volume	30
Issue number	10
DOIs	https://doi.org/10.1016/j.ymthe.2022.06.003
Publication status	Published - 5 Oct 2022

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10.1016/j.ymthe.2022.06.003

1-s2.0-S152500162200363X-mainFinal published version, 2.86 MBLicence: CC BY-NC-ND

Cite this

@article{8a9e9be07bb541ad8919c4ed123a2c22,

title = "MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson's disease",

author = "Marta Esteves and Ricardo Abreu and Hugo Fernandes and Catarina Serra-Almeida and Martins, {Patricia A. T.} and Marta Barao and Cristovao, {Ana Clara} and Claudia Saraiva and Raquel Ferreira and Lino Ferreira and Liliana Bernardino",

note = "Funding: This work was partially supported by the Portuguese “Funda{\c c}{\~a}o para a Ci{\^e}ncia e a Tecnologia (FCT)” through the ICON project (Interdisciplinary Challenges On Neurodegeneration; CENTRO-01-0145- FEDER-000013), projects 007630 UID/QUI/00313/2019 and POCI01-0145-FEDER-029919, co-funded by COMPETE2020-UE and CENTRO-01-0145-FEDER-000014 through “Programa Operacional Regional do Centro” CENTRO2020 and under doctoral grant SFRH/ BD/121822/2016; by the Interreg program, specifically the project “2IQBIONEURO: Impulso de una red de I + i en qu{\'i}mica biol{\'o}gica para diagn{\'o}stico y tratamiento de enfermedades neurol{\'o}gicas” (Ref: 1654) and NEUROATLANTIC entitled “An Atlantic innovation platform on diagnosis and treatment of neurological diseases and aging” (Ref: EAPA_791/2018). The authors also acknowledge the support of CICS-UBI and the PPBI-Portuguese Platform of BioImaging (POCI-01-0145-FEDER-022122).",

year = "2022",

month = oct,

day = "5",

doi = "10.1016/j.ymthe.2022.06.003",

language = "English",

volume = "30",

pages = "3176--3192",

journal = "Molecular Therapy",

issn = "1525-0016",

publisher = "Cell Press",

number = "10",

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TY - JOUR

T1 - MicroRNA-124-3p-enriched small extracellular vesicles as a therapeutic approach for Parkinson's disease

AU - Esteves, Marta

AU - Abreu, Ricardo

AU - Fernandes, Hugo

AU - Serra-Almeida, Catarina

AU - Martins, Patricia A. T.

AU - Barao, Marta

AU - Cristovao, Ana Clara

AU - Saraiva, Claudia

AU - Ferreira, Raquel

AU - Ferreira, Lino

AU - Bernardino, Liliana

N1 - Funding: This work was partially supported by the Portuguese “Fundação para a Ciência e a Tecnologia (FCT)” through the ICON project (Interdisciplinary Challenges On Neurodegeneration; CENTRO-01-0145- FEDER-000013), projects 007630 UID/QUI/00313/2019 and POCI01-0145-FEDER-029919, co-funded by COMPETE2020-UE and CENTRO-01-0145-FEDER-000014 through “Programa Operacional Regional do Centro” CENTRO2020 and under doctoral grant SFRH/ BD/121822/2016; by the Interreg program, specifically the project “2IQBIONEURO: Impulso de una red de I + i en química biológica para diagnóstico y tratamiento de enfermedades neurológicas” (Ref: 1654) and NEUROATLANTIC entitled “An Atlantic innovation platform on diagnosis and treatment of neurological diseases and aging” (Ref: EAPA_791/2018). The authors also acknowledge the support of CICS-UBI and the PPBI-Portuguese Platform of BioImaging (POCI-01-0145-FEDER-022122).

PY - 2022/10/5

Y1 - 2022/10/5

U2 - 10.1016/j.ymthe.2022.06.003

DO - 10.1016/j.ymthe.2022.06.003

M3 - Article

C2 - 35689381

SN - 1525-0016

VL - 30

SP - 3176

EP - 3192

JO - Molecular Therapy

JF - Molecular Therapy

IS - 10

ER -