TY - JOUR
T1 - Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases
AU - Malankowska, M.
AU - Martins, C. F.
AU - Rho, H. S.
AU - Neves, L. A.
AU - Tiggelaar, R. M.
AU - Crespo, J. G.
AU - Pina, María Pilar
AU - Mallada, R.
AU - Gardeniers, H.
AU - Coelhoso, I. M.
N1 - Sem PDF conforme despacho.
info:eu-repo/grantAgreement/FCT/5876/147218/PT#
The authors would like to acknowledge the financial support from the Government of Aragon and the Education, Audiovisual and Culture Executive Agency (EU-EACEA) within the EUDIME - "Erasmus Mundus Doctorate in Membrane Engineering" program (FPA 2011-0014, SGA 2012-1719, http://eudime.unical.it). CIBER-BBN is an initiative funded by the VI National R & D & i Plan 2008-2011 financed by the Instituto de Salud Carlos III European Regional Development Fund. Authors acknowledge the LMA-INA for offering access to their instruments and expertise. This work was also supported by the Associate Laboratory for Green Chemistry LAQV which is financed by national funds from FCT/MEC (UID/QUI/50006/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007265). Carla F. Martins acknowledge FCT for fellowship SFRH/BD/111128/2015 and Luisa A. Neves for the exploratory project grant IF/00505/2014/CP1224/CT0004 attributed within the 2014 FCT Researcher Program.
PY - 2018/1/1
Y1 - 2018/1/1
N2 - This work proposes a microfluidic gas – ionic liquid contactor for CO2 removal from anaesthesia gas, containing Xe. The working principle involves the transport of CO2 through a polymer flat membrane followed by its capture and enzymatic bioconversion in the ionic liquid solvent. Microfluidic devices enable a rapid and inexpensive screening of potential CO2 absorbers. The alveolar – type design of the ionic liquid chamber was adopted to reduce mass transfer limitations of CO2 through the liquid phase. Polydimethylsiloxane (PDMS) was the chosen polymer for dense membrane, as well as for the microfluidic device fabrication, mainly due to the high permeability of gases, O2 and CO2, and low cost. The selected ionic liquid was cholinium propionate (CP) with a water activity of 0.753, due to its high affinity towards CO2 and biocompatibility with the enzyme used for CO2 conversion to bicarbonate, carbonic anhydrase (CA). The CO2 and Xe permeability and CO2/Xe selectivity were determined in the microfluidic devices developed and compared to those exhibited by free standing PDMS membranes mounted on a standard permeation cell. The performance of the microfluidic devices as gas – ionic liquid contactors was evaluated for a given solvent flow rate with pure gas streams of CO2 and Xe. The obtained results show that cholinium propionate with or without the enzyme has no effect on the Xe transport, but remarkably enhances the affinity towards carbon dioxide leading to enhancement factor up to 1.9 in the presence of 0.1 mg CA/gIL.
AB - This work proposes a microfluidic gas – ionic liquid contactor for CO2 removal from anaesthesia gas, containing Xe. The working principle involves the transport of CO2 through a polymer flat membrane followed by its capture and enzymatic bioconversion in the ionic liquid solvent. Microfluidic devices enable a rapid and inexpensive screening of potential CO2 absorbers. The alveolar – type design of the ionic liquid chamber was adopted to reduce mass transfer limitations of CO2 through the liquid phase. Polydimethylsiloxane (PDMS) was the chosen polymer for dense membrane, as well as for the microfluidic device fabrication, mainly due to the high permeability of gases, O2 and CO2, and low cost. The selected ionic liquid was cholinium propionate (CP) with a water activity of 0.753, due to its high affinity towards CO2 and biocompatibility with the enzyme used for CO2 conversion to bicarbonate, carbonic anhydrase (CA). The CO2 and Xe permeability and CO2/Xe selectivity were determined in the microfluidic devices developed and compared to those exhibited by free standing PDMS membranes mounted on a standard permeation cell. The performance of the microfluidic devices as gas – ionic liquid contactors was evaluated for a given solvent flow rate with pure gas streams of CO2 and Xe. The obtained results show that cholinium propionate with or without the enzyme has no effect on the Xe transport, but remarkably enhances the affinity towards carbon dioxide leading to enhancement factor up to 1.9 in the presence of 0.1 mg CA/gIL.
KW - Anaesthesia gas recovery
KW - Carbon dioxide removal
KW - Carbonic anhydrase enzyme
KW - Cholinium-based ionic liquids
KW - Microfluidic membrane contactor
UR - http://www.scopus.com/inward/record.url?scp=85030163914&partnerID=8YFLogxK
U2 - 10.1016/j.memsci.2017.09.065
DO - 10.1016/j.memsci.2017.09.065
M3 - Article
AN - SCOPUS:85030163914
SN - 0376-7388
VL - 545
SP - 107
EP - 115
JO - Journal of Membrane Science
JF - Journal of Membrane Science
ER -