Methylene blue: A Trendy Photosensitizer in Medicine and in Solar-Energy Conversion Systems

Filipa Pires, Margarida Coelho, Paulo A. Ribeiro, Maria Raposo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The photosensitizer methylene blue (MB) has been investigated as a deoxyribonucleic acid (DNA) intercalant with the main objective of understanding the chemical/physical processes, which occur when adequate wavelength light is impinging on DNA intercalated with MB. This understanding is crucial for the creation of dynamic phototherapy procedures and for the development of new dye sensitized solar cells. During this work we developed and optimized all the conditions to efficiently produce [MB/DNA] multi-layered films by self-assembly. Our study revealed that pH strongly influences the growth of our multilayer films. Our UV studies revealed that the UV radiation causes damage of DNA through opening of aromatic ring and by breaking the DNA phosphate groups. The FT-IR studies on cast films with [MB/DNA] revealed that the denaturation ratio decreases as the irradiation increases, meaning that MB is an intercalant of DNA chain. This study paves the way to develop new dye sensitized solar cells which employ inexpensive materials and take advantage of the intercalation process in order to adjust the intermolecular arrangement of the donor/acceptor molecules to improve the device performance.

Original languageEnglish
Title of host publicationPHOTOPTICS 2016 - Proceedings of the 4th International Conference on Photonics, Optics and Laser Technology
PublisherSciTePress
Pages381-385
Number of pages5
ISBN (Electronic)9789897581748
Publication statusPublished - 2016
Event4th International Conference on Photonics, Optics and Laser Technology, PHOTOPTICS 2016 - Rome, Italy
Duration: 27 Feb 201629 Feb 2016

Conference

Conference4th International Conference on Photonics, Optics and Laser Technology, PHOTOPTICS 2016
CountryItaly
CityRome
Period27/02/1629/02/16

Keywords

  • DNA
  • Layer-by-layer
  • LbL
  • Methylene Blue
  • Photodynamic Therapy
  • Solar Cell
  • UV-Vis Spectroscopy

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