Abstract
An efficient method for the N‐arylation of primary and some secondary amines using 2‐halocyclohex‐2‐enones in an aliphatic‐to‐aromatic transformation in the presence of a substoichiometric amount of pTsOH has been developed. A series of arylamines have been synthesized from 2‐halocyclohex‐2‐enones by in situ enamine formation followed by aromatization under environmentally friendly conditions using pTsOH. This metal‐free, practical, relatively inexpensive protocol is of value in organic synthesis for industrial and academic applications.
| Original language | English |
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| Pages (from-to) | 742-747 |
| Journal | European Journal of Organic Chemistry |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Feb 2013 |