Metal-catalyzed cross-coupling reactions on azaindole synthesis and functionalization

A. Sofia Santos; Ana C. Mortinho; M. Manuel B. Marques

doi:10.3390/molecules23102673

Metal-catalyzed cross-coupling reactions on azaindole synthesis and functionalization

A. Sofia Santos, Ana C. Mortinho, M. Manuel B. Marques

Research output: Contribution to journal › Review article › peer-review

30 Citations (Scopus)

77 Downloads (Pure)

Abstract

Azaindoles are rare in nature but extremely attractive for drug discovery programs. Azaindoles can be obtained by diverse methods, including those involving metal-catalyzed reactions. This important core has been fascinating the scientific community due to their challenging synthesis and relevant bioactivity. This paper highlights the diverse synthetic methodologies developed to date involving metal-catalyzed reaction to attain azaindoles and its functionalization.

Original language	English
Article number	2673
Number of pages	16
Journal	Molecules
Volume	23
Issue number	10
DOIs	https://doi.org/10.3390/molecules23102673
Publication status	Published - 17 Oct 2018

Keywords

Azaindole
Cross-coupling reactions
Heterocycles
Metal-catalyzed

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10.3390/molecules23102673Licence: CC BY

Metal-Catalyzed Cross-Coupling Reactions onFinal published version, 3.89 MBLicence: CC BY

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title = "Metal-catalyzed cross-coupling reactions on azaindole synthesis and functionalization",

abstract = "Azaindoles are rare in nature but extremely attractive for drug discovery programs. Azaindoles can be obtained by diverse methods, including those involving metal-catalyzed reactions. This important core has been fascinating the scientific community due to their challenging synthesis and relevant bioactivity. This paper highlights the diverse synthetic methodologies developed to date involving metal-catalyzed reaction to attain azaindoles and its functionalization.",

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AU - Mortinho, Ana C.

AU - Marques, M. Manuel B.

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N2 - Azaindoles are rare in nature but extremely attractive for drug discovery programs. Azaindoles can be obtained by diverse methods, including those involving metal-catalyzed reactions. This important core has been fascinating the scientific community due to their challenging synthesis and relevant bioactivity. This paper highlights the diverse synthetic methodologies developed to date involving metal-catalyzed reaction to attain azaindoles and its functionalization.

AB - Azaindoles are rare in nature but extremely attractive for drug discovery programs. Azaindoles can be obtained by diverse methods, including those involving metal-catalyzed reactions. This important core has been fascinating the scientific community due to their challenging synthesis and relevant bioactivity. This paper highlights the diverse synthetic methodologies developed to date involving metal-catalyzed reaction to attain azaindoles and its functionalization.

KW - Azaindole

KW - Cross-coupling reactions

KW - Heterocycles

KW - Metal-catalyzed

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DO - 10.3390/molecules23102673

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VL - 23

JO - Molecules

JF - Molecules

IS - 10

M1 - 2673

ER -

Metal-catalyzed cross-coupling reactions on azaindole synthesis and functionalization

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