May sediment contamination be xenoestrogenic to benthic fish? A case study with Solea senegalensis

Cátia Gonçalves; Marta Susana Silvestre Gouveia Martins; Mário Emanuel Campos de Sousa Diniz; Maria Helena Ferrão Ribeiro da Costa; Sandra Caeiro; Pedro M. Costa

doi:10.1016/j.marenvres.2014.04.012

May sediment contamination be xenoestrogenic to benthic fish? A case study with Solea senegalensis

Cátia Gonçalves, Marta Susana Silvestre Gouveia Martins, Mário Emanuel Campos de Sousa Diniz, Maria Helena Ferrão Ribeiro da Costa, Sandra Caeiro, Pedro M. Costa

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Within an environmental risk assessment framework of a moderately contaminated estuary (the Sado, SW Portugal), the present work intended to detect endocrine disruption in a flatfish,Solea senegalensisKaup, 1858, and its potential relationship to organic toxicants. Animals were collected from two distinct areas in the estuary (industrial and rural) and from an external reference area. Hepatic vitellogenin (VTG) levels, cytochrome P450 (CYP1A) induction, ethoxyresorufin-O-deethylase (EROD) activity plus gonad histology were analysed. Males and females were sexually immature and showed no significant evidence of degenerative pathologies. However, hepatic VTG concentrations in males from the industrial area were higher than Reference, even reaching levels comparable to females, indicating low but measurable oestrogenic effects caused by the complex contaminant mixture in estuarine sediments. These individuals also presented elevated CYP1A induction and EROD activity, which is consistent with contamination by organic toxicants such as PAHs and other aryl hydrocarbon receptor (Ahr) -mediated toxicants.

Original language	English
Pages (from-to)	170–178
Journal	Marine Environmental Research
Volume	99
DOIs	https://doi.org/10.1016/j.marenvres.2014.04.012
Publication status	Published - Aug 2014

Keywords

CYP1A
EDCs
EROD
Flatfish
Mixtures
Pollution monitoring
Vitellogenin

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10.1016/j.marenvres.2014.04.012Licence: CC BY-NC-ND

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@article{cb011344328743bba6cfa13f5a774c2c,

title = "May sediment contamination be xenoestrogenic to benthic fish? A case study with Solea senegalensis",

abstract = "Within an environmental risk assessment framework of a moderately contaminated estuary (the Sado, SW Portugal), the present work intended to detect endocrine disruption in a flatfish,Solea senegalensisKaup, 1858, and its potential relationship to organic toxicants. Animals were collected from two distinct areas in the estuary (industrial and rural) and from an external reference area. Hepatic vitellogenin (VTG) levels, cytochrome P450 (CYP1A) induction, ethoxyresorufin-O-deethylase (EROD) activity plus gonad histology were analysed. Males and females were sexually immature and showed no significant evidence of degenerative pathologies. However, hepatic VTG concentrations in males from the industrial area were higher than Reference, even reaching levels comparable to females, indicating low but measurable oestrogenic effects caused by the complex contaminant mixture in estuarine sediments. These individuals also presented elevated CYP1A induction and EROD activity, which is consistent with contamination by organic toxicants such as PAHs and other aryl hydrocarbon receptor (Ahr) -mediated toxicants.",

keywords = "EROD, Mixtures, Flatfish, Pollution monitoring, EDCs, Vitellogenin, CYP1A, CYP1A , EDCs , EROD , Flatfish , Mixtures , Pollution monitoring , Vitellogenin",

author = "C{\'a}tia Gon{\c c}alves and Martins, {Marta Susana Silvestre Gouveia} and Diniz, {M{\'a}rio Emanuel Campos de Sousa} and Costa, {Maria Helena Ferr{\~a}o Ribeiro da} and Sandra Caeiro and Costa, {Pedro M.}",

note = "Sem PDF. P.M. Costa and M. Martins were supported by the Portuguese Science and Technology Foundation (FCT) through the grants SFRH/BPD/72564/2010 and SFRH/BD/64510/2009, respectively. The present research was financed by FCT and co-financed by the European Community FEDER through the program COMPETE (project reference PTDC/SAU-ESA/100107/2008). The authors thank C. Roque, I. Batalha and A. Pina (REQUIMTE); J. Lobo, A. Rodrigo, J. Antunes and S. Carreira (IMAR); G. Silva and L. Jacinto (Docapesca) and Mr and Mrs J. Bacalhau for their important assistance.",

year = "2014",

month = aug,

doi = "10.1016/j.marenvres.2014.04.012",

language = "English",

volume = "99",

pages = "170–178",

journal = "Marine Environmental Research",

issn = "0141-1136",

publisher = "Elsevier Science B.V., Amsterdam.",

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TY - JOUR

T1 - May sediment contamination be xenoestrogenic to benthic fish? A case study with Solea senegalensis

AU - Gonçalves, Cátia

AU - Martins, Marta Susana Silvestre Gouveia

AU - Diniz, Mário Emanuel Campos de Sousa

AU - Costa, Maria Helena Ferrão Ribeiro da

AU - Caeiro, Sandra

AU - Costa, Pedro M.

N1 - Sem PDF. P.M. Costa and M. Martins were supported by the Portuguese Science and Technology Foundation (FCT) through the grants SFRH/BPD/72564/2010 and SFRH/BD/64510/2009, respectively. The present research was financed by FCT and co-financed by the European Community FEDER through the program COMPETE (project reference PTDC/SAU-ESA/100107/2008). The authors thank C. Roque, I. Batalha and A. Pina (REQUIMTE); J. Lobo, A. Rodrigo, J. Antunes and S. Carreira (IMAR); G. Silva and L. Jacinto (Docapesca) and Mr and Mrs J. Bacalhau for their important assistance.

PY - 2014/8

Y1 - 2014/8

N2 - Within an environmental risk assessment framework of a moderately contaminated estuary (the Sado, SW Portugal), the present work intended to detect endocrine disruption in a flatfish,Solea senegalensisKaup, 1858, and its potential relationship to organic toxicants. Animals were collected from two distinct areas in the estuary (industrial and rural) and from an external reference area. Hepatic vitellogenin (VTG) levels, cytochrome P450 (CYP1A) induction, ethoxyresorufin-O-deethylase (EROD) activity plus gonad histology were analysed. Males and females were sexually immature and showed no significant evidence of degenerative pathologies. However, hepatic VTG concentrations in males from the industrial area were higher than Reference, even reaching levels comparable to females, indicating low but measurable oestrogenic effects caused by the complex contaminant mixture in estuarine sediments. These individuals also presented elevated CYP1A induction and EROD activity, which is consistent with contamination by organic toxicants such as PAHs and other aryl hydrocarbon receptor (Ahr) -mediated toxicants.

AB - Within an environmental risk assessment framework of a moderately contaminated estuary (the Sado, SW Portugal), the present work intended to detect endocrine disruption in a flatfish,Solea senegalensisKaup, 1858, and its potential relationship to organic toxicants. Animals were collected from two distinct areas in the estuary (industrial and rural) and from an external reference area. Hepatic vitellogenin (VTG) levels, cytochrome P450 (CYP1A) induction, ethoxyresorufin-O-deethylase (EROD) activity plus gonad histology were analysed. Males and females were sexually immature and showed no significant evidence of degenerative pathologies. However, hepatic VTG concentrations in males from the industrial area were higher than Reference, even reaching levels comparable to females, indicating low but measurable oestrogenic effects caused by the complex contaminant mixture in estuarine sediments. These individuals also presented elevated CYP1A induction and EROD activity, which is consistent with contamination by organic toxicants such as PAHs and other aryl hydrocarbon receptor (Ahr) -mediated toxicants.

KW - EROD

KW - Mixtures

KW - Flatfish

KW - Pollution monitoring

KW - EDCs

KW - Vitellogenin

KW - CYP1A

KW - EDCs

KW - EROD

KW - Flatfish

KW - Mixtures

KW - Pollution monitoring

KW - Vitellogenin

U2 - 10.1016/j.marenvres.2014.04.012

DO - 10.1016/j.marenvres.2014.04.012

M3 - Article

C2 - 24857782

SN - 0141-1136

VL - 99

SP - 170

EP - 178

JO - Marine Environmental Research

JF - Marine Environmental Research

ER -

May sediment contamination be xenoestrogenic to benthic fish? A case study with Solea senegalensis

Abstract

Keywords

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