Marine sesterterpenes: an overview

Patrícia Máximo; Ana Lourenço

doi:10.2174/1385272822666181029101212

Marine sesterterpenes: an overview

Research output: Contribution to journal › Review article

Abstract

Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as fungi, and in minor extent higher plants, lichens and insects. Sesterterpenes are diverse and these compounds display significant biological activities such as anti-inflammatory, cytotoxic, anticancer, antimicrobial, antitubercular, and anti-biofilm. This review presents the sesterterpenoid compounds identified from marine sources between 2013 and 2017. Structures are grouped as scalaranes, linear sesterterpenes and other sesterterpenes. Natural sources and reported biological activities are summarized in a table format.

Original language	English
Pages (from-to)	2381-2393
Number of pages	13
Journal	Current Organic Chemistry
Volume	22
Issue number	24
DOIs	https://doi.org/10.2174/1385272822666181029101212
Publication status	Published - 1 Jan 2018

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Keywords

Antiproliferative
Biological activity
Cytotoxic
Linear sesterterpenes norsesterterpenes
Natural products discovery
Scalaranes
Sesterterpenes

Cite this

Máximo, P., & Lourenço, A. (2018). Marine sesterterpenes: an overview. Current Organic Chemistry, 22(24), 2381-2393. https://doi.org/10.2174/1385272822666181029101212

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title = "Marine sesterterpenes: an overview",

abstract = "Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as fungi, and in minor extent higher plants, lichens and insects. Sesterterpenes are diverse and these compounds display significant biological activities such as anti-inflammatory, cytotoxic, anticancer, antimicrobial, antitubercular, and anti-biofilm. This review presents the sesterterpenoid compounds identified from marine sources between 2013 and 2017. Structures are grouped as scalaranes, linear sesterterpenes and other sesterterpenes. Natural sources and reported biological activities are summarized in a table format.",

keywords = "Antiproliferative, Biological activity, Cytotoxic, Linear sesterterpenes norsesterterpenes, Natural products discovery, Scalaranes, Sesterterpenes",

author = "Patr{\'i}cia M{\'a}ximo and Ana Louren{\cc}o",

note = "Authors Acknowledge the Associated Laboratory for Sustainable Chemistry - Clean Processes and Technologies LAQV, which is financed by national funds from FCT/MEC(UID/QUI/50006/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007265) for ensuring the conditions and means to carry out this work.",

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AU - Máximo, Patrícia

AU - Lourenço, Ana

N1 - Authors Acknowledge the Associated Laboratory for Sustainable Chemistry - Clean Processes and Technologies LAQV, which is financed by national funds from FCT/MEC(UID/QUI/50006/2013) and co-financed by the ERDF under the PT2020 Partnership Agreement (POCI-01-0145-FEDER-007265) for ensuring the conditions and means to carry out this work.

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N2 - Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as fungi, and in minor extent higher plants, lichens and insects. Sesterterpenes are diverse and these compounds display significant biological activities such as anti-inflammatory, cytotoxic, anticancer, antimicrobial, antitubercular, and anti-biofilm. This review presents the sesterterpenoid compounds identified from marine sources between 2013 and 2017. Structures are grouped as scalaranes, linear sesterterpenes and other sesterterpenes. Natural sources and reported biological activities are summarized in a table format.

AB - Sesterterpenes form a small group of terpenoids that are mainly present in the marine world although they are also produced by terrestrial organisms such as fungi, and in minor extent higher plants, lichens and insects. Sesterterpenes are diverse and these compounds display significant biological activities such as anti-inflammatory, cytotoxic, anticancer, antimicrobial, antitubercular, and anti-biofilm. This review presents the sesterterpenoid compounds identified from marine sources between 2013 and 2017. Structures are grouped as scalaranes, linear sesterterpenes and other sesterterpenes. Natural sources and reported biological activities are summarized in a table format.

KW - Antiproliferative

KW - Biological activity

KW - Cytotoxic

KW - Linear sesterterpenes norsesterterpenes

KW - Natural products discovery

KW - Scalaranes

KW - Sesterterpenes

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JF - Current Organic Chemistry

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