Management of childhood urticaria: Current knowledge and practical recommendations

Helena Pite, Bettina Wedi, Luís Miguel Borrego, Alexander Kapp, Ulrike Raap

Research output: Contribution to journalReview articlepeer-review

41 Citations (Scopus)
128 Downloads (Pure)


Urticaria, defined by the presence of wheals and/or angio edema, is a common condition in children, prompting parents to consult physicians. For its successful management, paediatric-specific features must be taken into account, regarding the identifcation of eliciting triggers and pharmacological therapy. This review systematically discusses the current best-available evidence on spontaneous acute and chronic urticaria as well as physical and other urticaria types in children. Potential underlying causes, namely infections, food and drug hypersensitivity, autoreactivity and autoimmune or other conditions, and eliciting stimuli are considered, with practical recommendations for specific diagnostic approaches. Second-generation antihistamines are the mainstay of pharmacological treatment aimed at relief of symptoms, which require dose adjustment for pae diatric use. Other therapeutic interventions are also discussed. In addition, unmet needs are highlighted, aiming to promote research into the paediatric population, ultimately aiming at the effective management of childhood urticaria.

Original languageEnglish
Pages (from-to)500-508
Number of pages9
JournalActa Dermato-Venereologica
Issue number5
Publication statusPublished - 2013


  • Antihistamines
  • Children
  • Diagnosis
  • Disease management
  • Pruritus
  • Therapy
  • Urticaria


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