Malaria combination therapies: Advantages and shortcomings

A. Martinelli; R. Moreira; P. V.L. Cravo

doi:10.2174/138955708783744092

Malaria combination therapies: Advantages and shortcomings

A. Martinelli, R. Moreira, P. V.L. Cravo

Research output: Contribution to journal › Review article

34 Citations (Scopus)

Abstract

Drug combination therapies have been devised to delay the development and spread of resistant malaria parasites. However, poor design often leads to ineffective combinations. Here, the properties of various drug combinations are reviewed in relationship to drug resistance and their pharmacokinetic compatibility.

Original language	English
Pages (from-to)	201-212
Number of pages	12
Journal	Mini-Reviews in Medicinal Chemistry
Volume	8
Issue number	3
DOIs	https://doi.org/10.2174/138955708783744092
Publication status	Published - 1 Mar 2008

Keywords

Antifolates
Artemisinin
Drug combination therapy
Drug resistance
Malaria
Quinolines

UN Sustainable Development Goals (SDGs)

SDG 3 - Good Health and Well-Being

Access to Document

10.2174/138955708783744092

Link to publication in Scopus

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AU - Cravo, P. V.L.

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KW - Drug resistance

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KW - Quinolines

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