Magnetic separations in biotechnology

Luis Borlido, Ana M. Azevedo, Ana Cecília Afonso Roque, Maria Raquel Aires-Barros

Research output: Contribution to journalArticlepeer-review

147 Citations (Scopus)

Abstract

Magnetic separations are probably one of the most versatile separation processes in biotechnology as they are able to purify cells, viruses, proteins and nucleic acids directly from crude samples. The fast and gentle process in combination with its easy scale-up and automation provide unique advantages over other separation techniques. In the midst of this process are the magnetic adsorbents tailored for the envisioned target and whose complex synthesis spans over multiple fields of science. In this context, this article reviews both the synthesis and tailoring of magnetic adsorbents for bioseparations as well as their ultimate application.
Original languageEnglish
Pages (from-to)1374–1385
JournalBiotechnology Advances
Volume31
Issue number8
DOIs
Publication statusPublished - 2013

Keywords

  • Magnetic particles
  • Magnetic separations
  • Synthesis
  • Purification
  • Automation

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