Magnetic, fluorescent and hybrid nanoparticles: From synthesis to application in biosystems

Research output: Contribution to journalReview article

Abstract

Multifunctional nanoparticles have emerged as an outstanding candidate for a new generation of biomedical applications, mainly due to their remarkable properties and biocompatibility. Individual reports on multi-metal, semiconducting and superparamagnetic nanoparticles (SPIONs), elucidating on each's unique intrinsic properties, have demonstrated that the biological application of such materials is highly dependent of their size, shape, surface nature and core nature. However, reviews combining nanoparticles with multiple properties, as fluorescence and paramagnetism, as well as, biocompatibility, toxicology and biodegradability are yet seldom. This review highlights the highest output advances, of the last decade, on synthetic procedures for the design of multifunctional magneto-luminescent hybrid nanosystems based on quantum dots, SPIONs and mesoporous silica nanoparticles, as well as, surface modifications and their role for biological applications.

Original languageEnglish
Article number110104
JournalMaterials Science and Engineering C
Volume106
DOIs
Publication statusPublished - 1 Jan 2020

Fingerprint

Nanoparticles
nanoparticles
biocompatibility
synthesis
Biocompatibility
toxicology
Nanosystems
Paramagnetism
biodegradability
paramagnetism
Biodegradability
Silicon Dioxide
Semiconductor quantum dots
Surface treatment
Metals
Fluorescence
Silica
quantum dots
silicon dioxide
fluorescence

Keywords

  • Fluorescence
  • Imaging
  • Multifunctionality
  • Nanoparticles
  • Silicon quantum dots
  • SPIONs

Cite this

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title = "Magnetic, fluorescent and hybrid nanoparticles: From synthesis to application in biosystems",
abstract = "Multifunctional nanoparticles have emerged as an outstanding candidate for a new generation of biomedical applications, mainly due to their remarkable properties and biocompatibility. Individual reports on multi-metal, semiconducting and superparamagnetic nanoparticles (SPIONs), elucidating on each's unique intrinsic properties, have demonstrated that the biological application of such materials is highly dependent of their size, shape, surface nature and core nature. However, reviews combining nanoparticles with multiple properties, as fluorescence and paramagnetism, as well as, biocompatibility, toxicology and biodegradability are yet seldom. This review highlights the highest output advances, of the last decade, on synthetic procedures for the design of multifunctional magneto-luminescent hybrid nanosystems based on quantum dots, SPIONs and mesoporous silica nanoparticles, as well as, surface modifications and their role for biological applications.",
keywords = "Fluorescence, Imaging, Multifunctionality, Nanoparticles, Silicon quantum dots, SPIONs",
author = "Marcelo, {Gon{\cc}alo A.} and Carlos Lodeiro and Capelo, {Jos{\'e} Luis} and Julia Lorenzo and Elisabete Oliveira",
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T1 - Magnetic, fluorescent and hybrid nanoparticles: From synthesis to application in biosystems

AU - Marcelo, Gonçalo A.

AU - Lodeiro, Carlos

AU - Capelo, José Luis

AU - Lorenzo, Julia

AU - Oliveira, Elisabete

PY - 2020/1/1

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N2 - Multifunctional nanoparticles have emerged as an outstanding candidate for a new generation of biomedical applications, mainly due to their remarkable properties and biocompatibility. Individual reports on multi-metal, semiconducting and superparamagnetic nanoparticles (SPIONs), elucidating on each's unique intrinsic properties, have demonstrated that the biological application of such materials is highly dependent of their size, shape, surface nature and core nature. However, reviews combining nanoparticles with multiple properties, as fluorescence and paramagnetism, as well as, biocompatibility, toxicology and biodegradability are yet seldom. This review highlights the highest output advances, of the last decade, on synthetic procedures for the design of multifunctional magneto-luminescent hybrid nanosystems based on quantum dots, SPIONs and mesoporous silica nanoparticles, as well as, surface modifications and their role for biological applications.

AB - Multifunctional nanoparticles have emerged as an outstanding candidate for a new generation of biomedical applications, mainly due to their remarkable properties and biocompatibility. Individual reports on multi-metal, semiconducting and superparamagnetic nanoparticles (SPIONs), elucidating on each's unique intrinsic properties, have demonstrated that the biological application of such materials is highly dependent of their size, shape, surface nature and core nature. However, reviews combining nanoparticles with multiple properties, as fluorescence and paramagnetism, as well as, biocompatibility, toxicology and biodegradability are yet seldom. This review highlights the highest output advances, of the last decade, on synthetic procedures for the design of multifunctional magneto-luminescent hybrid nanosystems based on quantum dots, SPIONs and mesoporous silica nanoparticles, as well as, surface modifications and their role for biological applications.

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KW - Imaging

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KW - Silicon quantum dots

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