TY - JOUR
T1 - Magnetic, fluorescent and hybrid nanoparticles: From synthesis to application in biosystems
AU - Marcelo, Gonçalo A.
AU - Lodeiro, Carlos
AU - Capelo, José Luis
AU - Lorenzo, Julia
AU - Oliveira, Elisabete
N1 - info:eu-repo/grantAgreement/FCT/5876/147218/PT#
POCI-01-0145-FEDER - 007265.
PD/BD/142865/2018.
CEECIND/00648/2017.
Sem PDF conforme despacho.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - Multifunctional nanoparticles have emerged as an outstanding candidate for a new generation of biomedical applications, mainly due to their remarkable properties and biocompatibility. Individual reports on multi-metal, semiconducting and superparamagnetic nanoparticles (SPIONs), elucidating on each's unique intrinsic properties, have demonstrated that the biological application of such materials is highly dependent of their size, shape, surface nature and core nature. However, reviews combining nanoparticles with multiple properties, as fluorescence and paramagnetism, as well as, biocompatibility, toxicology and biodegradability are yet seldom. This review highlights the highest output advances, of the last decade, on synthetic procedures for the design of multifunctional magneto-luminescent hybrid nanosystems based on quantum dots, SPIONs and mesoporous silica nanoparticles, as well as, surface modifications and their role for biological applications.
AB - Multifunctional nanoparticles have emerged as an outstanding candidate for a new generation of biomedical applications, mainly due to their remarkable properties and biocompatibility. Individual reports on multi-metal, semiconducting and superparamagnetic nanoparticles (SPIONs), elucidating on each's unique intrinsic properties, have demonstrated that the biological application of such materials is highly dependent of their size, shape, surface nature and core nature. However, reviews combining nanoparticles with multiple properties, as fluorescence and paramagnetism, as well as, biocompatibility, toxicology and biodegradability are yet seldom. This review highlights the highest output advances, of the last decade, on synthetic procedures for the design of multifunctional magneto-luminescent hybrid nanosystems based on quantum dots, SPIONs and mesoporous silica nanoparticles, as well as, surface modifications and their role for biological applications.
KW - Fluorescence
KW - Imaging
KW - Multifunctionality
KW - Nanoparticles
KW - Silicon quantum dots
KW - SPIONs
UR - http://www.scopus.com/inward/record.url?scp=85071980254&partnerID=8YFLogxK
U2 - 10.1016/j.msec.2019.110104
DO - 10.1016/j.msec.2019.110104
M3 - Review article
AN - SCOPUS:85071980254
SN - 0928-4931
VL - 106
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
M1 - 110104
ER -