Longstanding presence of HIV-2 infection in Guinea-Bissau (West Africa)

J Piedade, Teresa Venenno, Emília Prieto, Rita Albuquerque, A Esteves, R Parreira, W. Canas-Ferreira

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8 Citations (Scopus)


We have retrospectively studied the seroprevalence of the human immunodeficiency virus (HIV) in Guinea-Bissau in a sample of sera collected from the whole country in 1980. We tested a total of 1248 individuals and found 11 individuals who were seropositive for HIV-2 but there were no HIV-1 seropositive samples. The mean age of the HIV-2 seropositive people was significantly higher than the age of the seronegative individuals. In the different areas surveyed, the HIV-2 seroprevalence ranged from 0 to 2.5%. A central region of the country, grossly centred in the capital city of Bissau, presented the highest prevalence of HIV-2 seropositivity (> 2%), which contrasts with its virtual absence from the more remote rural areas located near the borders with the neighbouring countries. The overall seroprevalence found for HIV-2 in this study is 0.9% (1.8%, when considering the adult seroprevalence only), which proves that the virus was definitely circulating in Guinea-Bissau at the beginning of the 1980s.
Original languageEnglish
Pages (from-to)119-124
Number of pages6
JournalActa Tropica
Issue number2
Publication statusPublished - 18 Sep 2000


  • Guinea-Bissau
  • HIV-2
  • West Africa


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