Carcinomatose leptomeníngea num doente com adenocarcinoma do pulmão tratada com radioterapia holocraniana e quimioterapia intratecal

Translated title of the contribution: Leptomeningeal carcinomatosis in a patient with lung adenocarcinoma treated with whole brain radiation therapy and intrathecal chemotherapy

Urmik Mohanlal, Duarte Salgado

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Abstract

Leptomeningeal carcinomatosis is a rare complication of several types of cancer. There are many possible clinical features, and the diagnosis is made with brain imaging and cytological analysis of cerebrospinal fluid. Treatment is widely debated and, concerning overall survival, there does not seem to exist a treatment option which is definitely superior. The present work describes the case of a 53-year-old man diagnosed with leptomeningeal carcinomatosis secondary to lung adenocarcinoma, who was treated with whole brain radiation therapy and, upon relapse, with intrathecal chemotherapy, showing both an above-average overall survival and a high performance status.

Translated title of the contributionLeptomeningeal carcinomatosis in a patient with lung adenocarcinoma treated with whole brain radiation therapy and intrathecal chemotherapy
Original languagePortuguese
Pages (from-to)50-53
Number of pages4
JournalSinapse
Volume21
Issue number1
DOIs
Publication statusPublished - 1 Jan 2021

Keywords

  • Antineoplastic agents/ therapeutic use
  • Cranial irradiation
  • Lung neoplasms
  • Meningeal carcinomatosis

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