L2A5 Antibody or functional fragment thereof against tumour antigens

Paula Alexandra Quintela Videira; Carlos Manuel Mendes Novo; Liliana Raquel Rodrigues Loureiro; Mylène Adelaide do Rosário Carrascal; José Alexandre Ribeiro de Castro Ferreira; Maria Angelina de Sá Palma; Lúcio Lara Santos; Luís Carlos Oliveira Lima; Wengang Chai; Michael Bachmann

L2A5 Antibody or functional fragment thereof against tumour antigens

Paula Alexandra Quintela Videira (Inventor), Carlos Manuel Mendes Novo (Inventor), Liliana Raquel Rodrigues Loureiro (Inventor), Mylène Adelaide do Rosário Carrascal (Inventor), José Alexandre Ribeiro de Castro Ferreira (Inventor), Maria Angelina de Sá Palma (Inventor), Lúcio Lara Santos (Inventor), Luís Carlos Oliveira Lima (Inventor), Wengang Chai (Inventor), Michael Bachmann (Inventor)

Research output: Patent › International PCT application

Abstract

This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/ amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.

Original language	English
Patent number	WO2019147152
IPC	G01N 33/ 574 A I
Priority date	26/01/18
Filing date	17/01/19
Publication status	Published - 1 Aug 2019

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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title = "L2A5 Antibody or functional fragment thereof against tumour antigens",

abstract = "This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/ amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.",

author = "Videira, \{Paula Alexandra Quintela\} and Novo, \{Carlos Manuel Mendes\} and Loureiro, \{Liliana Raquel Rodrigues\} and Carrascal, \{Myl{\`e}ne Adelaide do Ros{\'a}rio\} and Ferreira, \{Jos{\'e} Alexandre Ribeiro de Castro\} and Palma, \{Maria Angelina de S{\'a}\} and Santos, \{L{\'u}cio Lara\} and Lima, \{Lu{\'i}s Carlos Oliveira\} and Wengang Chai and Michael Bachmann",

year = "2019",

month = aug,

day = "1",

language = "English",

type = "Patent",

note = "WO2019147152; G01N 33/ 574 A I",

}

TY - PAT

T1 - L2A5 Antibody or functional fragment thereof against tumour antigens

AU - Videira, Paula Alexandra Quintela

AU - Novo, Carlos Manuel Mendes

AU - Loureiro, Liliana Raquel Rodrigues

AU - Carrascal, Mylène Adelaide do Rosário

AU - Ferreira, José Alexandre Ribeiro de Castro

AU - Palma, Maria Angelina de Sá

AU - Santos, Lúcio Lara

AU - Lima, Luís Carlos Oliveira

AU - Chai, Wengang

AU - Bachmann, Michael

PY - 2019/8/1

Y1 - 2019/8/1

N2 - This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/ amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.

AB - This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/ amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.

M3 - International PCT application

M1 - WO2019147152

Y2 - 2019/01/17

ER -

L2A5 Antibody or functional fragment thereof against tumour antigens

Abstract

UN SDGs

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