TY - PAT
T1 - L2A5 Antibody or functional fragment thereof against tumour antigens
AU - Videira, Paula Alexandra Quintela
AU - Novo, Carlos Manuel Mendes
AU - Loureiro, Liliana Raquel Rodrigues
AU - Carrascal, Mylène Adelaide do Rosário
AU - Ferreira, José Alexandre Ribeiro de Castro
AU - Palma, Maria Angelina de Sá
AU - Santos, Lúcio Lara
AU - Lima, Luís Carlos Oliveira
AU - Chai, Wengang
AU - Bachmann, Michael Philippe
PY - 2020/12/2
Y1 - 2020/12/2
N2 - This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/ amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.
AB - This invention provides an antibody or functional antibody fragments, or probe thereof directed against a unique group of antigens identified in cancer. The present invention comprises nucleotide sequences derived from L2A5 monoclonal antibody. The antibody or functional antibody fragment, or probe thereof includes a variable heavy chain domain and a variable light chain domain that has an amino acid sequence provided herein. This DNA/ amino acid sequence conjugation is unique and has never been described before. The present invention further provides antibody or functional antibody fragment or a conjugate or a recombinant protein useful in the detection, treatment and prevention of human disease, including cancer.
M3 - Regional/Other National Application
M1 - EP3743726
Y2 - 2020/08/26
ER -
