Isolation and identification of antioxidants from Pedilanthus tithymaloides

Pedro Jorge Macedo de Abreu; Susan Matthew; Tania López González; Lucie Pompeiano Vaníčková; David Costa; Ana F. R. Gomes; Marcela A. Segundo; Eduarda Fernandes

doi:10.1007/s11418-007-0186-z

Isolation and identification of antioxidants from Pedilanthus tithymaloides

Pedro Jorge Macedo de Abreu, Susan Matthew, Tania López González, Lucie Pompeiano Vaníčková, David Costa, Ana F. R. Gomes, Marcela A. Segundo, Eduarda Fernandes

Research output: Contribution to journal › Article › peer-review

27 Citations (Scopus)

Abstract

A bioassay-guided methodology utilizing 2,2-diphenyl-1-picrylhydrazyl (DPPH), the trolox equivalent antioxidant capacity (TEAC), and reducing power assays, as well as an assessment of scavenging properties against O ₂^.- , H₂O₂, HOCl, ROO·, ·NO, and ONOO^- were used to find the main antioxidant principles of Pedilanthus tithymaloides (Euphorbiaceae), a shrub used in traditional Cuban medicine. The principles were identified as kaempferol 3-O-β-D-glucopyranoside-6″-(3-hydroxy-3-methylglutarate), quercitrin, isoquercitrin, and scopoletin. The contents of total phenolics and flavonoids were found to be 76.0 ± 4.8 mg of gallic acid equivalents/g extract and 9.8 ± 0.4 mg of rutin equivalents/g extract, respectively.

Original language	English
Pages (from-to)	67-70
Number of pages	4
Journal	Journal Of Natural Medicines
Volume	62
Issue number	1
DOIs	https://doi.org/10.1007/s11418-007-0186-z
Publication status	Published - Jan 2008

Keywords

Anti-inflammatory activity
Antioxidant activity
Coumarin
Flavonoid
Pedilanthus tithymaloides

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title = "Isolation and identification of antioxidants from Pedilanthus tithymaloides",

abstract = "A bioassay-guided methodology utilizing 2,2-diphenyl-1-picrylhydrazyl (DPPH), the trolox equivalent antioxidant capacity (TEAC), and reducing power assays, as well as an assessment of scavenging properties against O 2.- , H2O2, HOCl, ROO·, ·NO, and ONOO- were used to find the main antioxidant principles of Pedilanthus tithymaloides (Euphorbiaceae), a shrub used in traditional Cuban medicine. The principles were identified as kaempferol 3-O-β-D-glucopyranoside-6″-(3-hydroxy-3-methylglutarate), quercitrin, isoquercitrin, and scopoletin. The contents of total phenolics and flavonoids were found to be 76.0 ± 4.8 mg of gallic acid equivalents/g extract and 9.8 ± 0.4 mg of rutin equivalents/g extract, respectively.",

keywords = "Anti-inflammatory activity, Antioxidant activity, Coumarin, Flavonoid, Pedilanthus tithymaloides",

author = "Abreu, \{Pedro Jorge Macedo de\} and Susan Matthew and Gonz{\'a}lez, \{Tania L{\'o}pez\} and Van{\'i}{\v c}kov{\'a}, \{Lucie Pompeiano\} and David Costa and Gomes, \{Ana F. R.\} and Segundo, \{Marcela A.\} and Eduarda Fernandes",

year = "2008",

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doi = "10.1007/s11418-007-0186-z",

language = "English",

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AU - Abreu, Pedro Jorge Macedo de

AU - Matthew, Susan

AU - González, Tania López

AU - Vaníčková, Lucie Pompeiano

AU - Costa, David

AU - Gomes, Ana F. R.

AU - Segundo, Marcela A.

AU - Fernandes, Eduarda

PY - 2008/1

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AB - A bioassay-guided methodology utilizing 2,2-diphenyl-1-picrylhydrazyl (DPPH), the trolox equivalent antioxidant capacity (TEAC), and reducing power assays, as well as an assessment of scavenging properties against O 2.- , H2O2, HOCl, ROO·, ·NO, and ONOO- were used to find the main antioxidant principles of Pedilanthus tithymaloides (Euphorbiaceae), a shrub used in traditional Cuban medicine. The principles were identified as kaempferol 3-O-β-D-glucopyranoside-6″-(3-hydroxy-3-methylglutarate), quercitrin, isoquercitrin, and scopoletin. The contents of total phenolics and flavonoids were found to be 76.0 ± 4.8 mg of gallic acid equivalents/g extract and 9.8 ± 0.4 mg of rutin equivalents/g extract, respectively.

KW - Anti-inflammatory activity

KW - Antioxidant activity

KW - Coumarin

KW - Flavonoid

KW - Pedilanthus tithymaloides

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DO - 10.1007/s11418-007-0186-z

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JO - Journal Of Natural Medicines

JF - Journal Of Natural Medicines

IS - 1

ER -

Isolation and identification of antioxidants from Pedilanthus tithymaloides

Abstract

Keywords

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