Abstract
Analysis of lacrimal fluid is under attention of scientists and physicians as an open "window" for non-invasive assessment to relevant information about the health status. In the present work we propose an innovative method for the analysis of volatile metabolites present in the lacrimal fluid by non-invasive, fast and inexpensive technique: Ion Mobility Spectrometry coupled to a Multi-Capillary Column (MCC-IMS). Experimental protocol for lacrimal fluid collection and its further analysis by MCC-IMS was developed. For the first time this technology was used for the analysis of tears from healthy and diabetic person for a "proof of concept" purpose. Obtained experimental result showed that proposed method is suitable for the sensitive in-situ express analysis of Volatile Organic Compounds (VOCs) from lacrimal fluid and have a promising diagnostic potential.
| Original language | English |
|---|---|
| Title of host publication | BIODEVICES 2013 |
| Subtitle of host publication | Proceedings of the International Conference on Biomedical Electronics and Devices: February 11-14, 2013, in Barcelona, Spain |
| Editors | Mireya Fernández Chimeno, Jordi Solé-Casals, Ana Fred, Hugo Gamboa |
| Place of Publication | Setúbal |
| Publisher | SciTePress - Science and Technology Publications |
| Pages | 220-224 |
| Number of pages | 5 |
| Volume | 1 |
| ISBN (Print) | 978-989-8565-34-1 |
| DOIs | |
| Publication status | Published - 2013 |
| Event | International Conference on Biomedical Electronics and Devices, BIODEVICES 2013 - Barcelona, Spain Duration: 11 Feb 2013 → 14 Feb 2013 |
Conference
| Conference | International Conference on Biomedical Electronics and Devices, BIODEVICES 2013 |
|---|---|
| Country/Territory | Spain |
| City | Barcelona |
| Period | 11/02/13 → 14/02/13 |
Keywords
- Diagnostic
- Ion Mobility Spectrometry
- Lacrimal Fluid
- MCC-IMS
- VOCs
- Volatile Organic Compounds
