Instrumental tools for express analysis of lacrimal fluids

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2 Citations (Scopus)


Analysis of lacrimal fluid is under attention of scientists and physicians as an open "window" for non-invasive assessment to relevant information about the health status. In the present work we propose an innovative method for the analysis of volatile metabolites present in the lacrimal fluid by non-invasive, fast and inexpensive technique: Ion Mobility Spectrometry coupled to a Multi-Capillary Column (MCC-IMS). Experimental protocol for lacrimal fluid collection and its further analysis by MCC-IMS was developed. For the first time this technology was used for the analysis of tears from healthy and diabetic person for a "proof of concept" purpose. Obtained experimental result showed that proposed method is suitable for the sensitive in-situ express analysis of Volatile Organic Compounds (VOCs) from lacrimal fluid and have a promising diagnostic potential.

Original languageEnglish
Title of host publicationBIODEVICES 2013
Subtitle of host publicationProceedings of the International Conference on Biomedical Electronics and Devices: February 11-14, 2013, in Barcelona, Spain
EditorsMireya Fernández Chimeno, Jordi Solé-Casals, Ana Fred, Hugo Gamboa
Place of PublicationSetúbal
PublisherSciTePress - Science and Technology Publications
Number of pages5
ISBN (Print)978-989-8565-34-1
Publication statusPublished - 2013
EventInternational Conference on Biomedical Electronics and Devices, BIODEVICES 2013 - Barcelona, Spain
Duration: 11 Feb 201314 Feb 2013


ConferenceInternational Conference on Biomedical Electronics and Devices, BIODEVICES 2013


  • Diagnostic
  • Ion Mobility Spectrometry
  • Lacrimal Fluid
  • VOCs
  • Volatile Organic Compounds


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