TY - CHAP
T1 - Increased Abdominal Perimeter Differently Affects Respiratory Function in Men and Women
AU - Sacramento, Joana F.
AU - Caires, Iolanda
AU - Guarino, Maria P.
AU - Ribeiro, Maria J.
AU - Santiago, João C.P.
AU - Timóteo, Ana T.
AU - Selas, Mafalda
AU - Mota-Carmo, Miguel
AU - Conde, Silvia V.
N1 - Funding Information:
This work was funded with a grant from the Portuguese Foundation for Science and Technology (FCT) with the reference PTDC/SAU-ORG/111417/2009. JFS is supported by a contract from FCT with the reference CEEC IND/02428/2018. We deeply thank Prof. Miguel Mota Carmo for his enormous support to the Neuronal Control of Metabolic Disturbances Research Group (NeuroMetab.Lab). He passed away during the development of this project which would never have happened without his dedication.
Funding Information:
Acknowledgments This work was funded with a grant from the Portuguese Foundation for Science and Technology (FCT) with the reference PTDC/SAU- circumference (women ≥80 cm and men ≥94 cm). Data represent the mean ± SEM of 25 women and 12 men sub - jects. Student’s t test: p < 0.01 comparing with normal abdominal circumference ORG/111417/2009. JFS is supported by a contract from FCT with the reference CEEC IND/02428/2018.
Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2023.
PY - 2023
Y1 - 2023
N2 - Obesity is a worldwide epidemic being the main cause of cardiovascular, metabolic disturbances and chronic pulmonary diseases. The increase in body weight may affect the respiratory system due to fat deposition and systemic inflammation. Herein, we evaluated the sex differences in the impact of obesity and high abdominal circumference on basal ventilation. Thirty-five subjects, 23 women and 12 men with a median age of 61 and 67, respectively, were studied and classified as overweight and obese according to body mass index (BMI) and were also divided by the abdominal circumference. Basal ventilation, namely, respiratory frequency, tidal volume, and minute ventilation, was evaluated. In nor-mal and overweight women, basal ventilation did not change, but obese women exhibited a decrease in tidal volume. In men, overweight and obese subjects did not exhibit altered basal ventilation. In contrast, when subjects were subdivided based on the abdominal perimeter, a higher circumference did not change the respiratory frequency but induced a decrease in tidal volume and minute ventilation in women, while in men these two param-eters increased. In conclusion, higher abdominal circumference rather than BMI is associated with alterations in basal ventilation in women and men.
AB - Obesity is a worldwide epidemic being the main cause of cardiovascular, metabolic disturbances and chronic pulmonary diseases. The increase in body weight may affect the respiratory system due to fat deposition and systemic inflammation. Herein, we evaluated the sex differences in the impact of obesity and high abdominal circumference on basal ventilation. Thirty-five subjects, 23 women and 12 men with a median age of 61 and 67, respectively, were studied and classified as overweight and obese according to body mass index (BMI) and were also divided by the abdominal circumference. Basal ventilation, namely, respiratory frequency, tidal volume, and minute ventilation, was evaluated. In nor-mal and overweight women, basal ventilation did not change, but obese women exhibited a decrease in tidal volume. In men, overweight and obese subjects did not exhibit altered basal ventilation. In contrast, when subjects were subdivided based on the abdominal perimeter, a higher circumference did not change the respiratory frequency but induced a decrease in tidal volume and minute ventilation in women, while in men these two param-eters increased. In conclusion, higher abdominal circumference rather than BMI is associated with alterations in basal ventilation in women and men.
KW - Abdominal circumference
KW - Basal ventilation
KW - Obesity
KW - Overweight
UR - http://www.scopus.com/inward/record.url?scp=85163274265&partnerID=8YFLogxK
U2 - 10.1007/978-3-031-32371-3_15
DO - 10.1007/978-3-031-32371-3_15
M3 - Chapter
C2 - 37322344
AN - SCOPUS:85163274265
T3 - Advances in Experimental Medicine and Biology
SP - 135
EP - 141
BT - Advances in Experimental Medicine and Biology
PB - Springer
ER -
