Importance of tissue sampling, laboratory methods, and patient characteristics for detection of Pneumocystis in autopsied lungs of non-immunosuppressed individuals

S. L. Vargas, C. Ponce, R. Bustamante, E. Calderón, G. Nevez, Y. De Armas, O. Matos, R. F. Miller, M. J. Gallo

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

To understand the epidemiological significance of Pneumocystis detection in a lung tissue sample of non-immunosuppressed individuals, we examined sampling procedures, laboratory methodology, and patient characteristics of autopsy series reported in the literature. Number of tissue specimens, DNA-extraction procedures, age and underlying diagnosis highly influence yield and are critical to understand yield differences of Pneumocystis among reports of pulmonary colonization in immunocompetent individuals.

Original languageEnglish
Pages (from-to)1711-1716
Number of pages6
JournalEuropean Journal of Clinical Microbiology and Infectious Diseases
Volume36
Issue number10
DOIs
Publication statusPublished - 1 Oct 2017

Keywords

  • INFANT-DEATH-SYNDROME
  • F-SP HOMINIS
  • GENERAL-POPULATION
  • CARINII-PNEUMONIA
  • JIROVECII DNA
  • COLONIZATION
  • INFECTION

UN Sustainable Development Goals (Under maintenance)

  • SDG 3 - Good Health and Well-Being

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