Implementation and operational research: epidemiology and prevention: computer-assisted intervention for safer sex in HIV-positive men having sex with men: findings of a European randomized multi-center trial

Christiana Nöstlinger, Tom Platteau, J. R. Bogner, J Buyze, Joanna Dec-Pietrowska, S Dias, J Newbury-Helps, A Kocsis, M. Mueller, D Rojas , Danika Stanekova, J van Lankveld, R Colebunders

Research output: Contribution to journalArticle

Abstract


OBJECTIVE:
Men who have sex with men (MSM) are the key population most affected by HIV in Europe. We performed the first European multicenter, simple-randomized parallel-group study to test the effectiveness of a theory-guided computer-assisted intervention to improve safer sex among HIV-positive men who have sex with men.

METHODS:
Between February, 2011 and February, 2013, 112 participants were enrolled in 8 different European HIV-care settings. Intervention participants received 3 individual counseling sessions facilitated by trained service providers using computer-assisted tools. The control-group received sexual health advice delivered as part of regular HIV care. Outcome behavior (self-reported condom use at last intercourse; combined HIV transmission risk score), its influencing factors, and mediating variables were assessed at baseline, and at 3 and 6 months follow-up. Mixed effects models were used to compare primary outcomes (condom use at last intercourse, HIV transmission risk score), and mediation analysis to explore intervention effects.

RESULTS:
Condom use at last intercourse increased more among intervention than control participants at 3 months follow-up (odds ratio of 3.83; P = 0.03), but not significantly at 6 months follow-up. Intervention participants reported a lower transmission risk at 3 months follow-up than controls (odds ratio compared with baseline of 11.53 and 1.28, respectively; P = 0.008), but this effect became nonsignificant at 6 months. Intervention effects were mediated by the proximal variables, self-efficacy to negotiate condom use and condom attitudes.

CONCLUSIONS:
This intervention showed short-term effectiveness. The intervention should be replicated in other settings, eventually investigating if booster-counseling sessions would yield a longer lasting effect.
Original languageEnglish
Pages (from-to)e63-e72
Number of pages9
JournalJournal of Acquired Immune Deficiency Syndromes
VolumeVol. 71
Issue numbern.º 3
DOIs
Publication statusPublished - 1 Mar 2016

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