IgG and IgM Antibodies Immunoreacting with a 2,3-Diacyl Trehalose-2′-sulphate in Sera from Leprosy Patients

Philippe Cruaud, Marie Christine Potar, Hugo L. David, Fernand Papa, Jorge Torgal-Garcia, Fatima Maroja, Ana Tereza Orsi-Souza

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Abstract

The distribution of IgG and IgM antibodies immunoreacting with the sulpholipid I (SLI) and sulpholipid IV (SLIV) of Mycobacterium tuberculosis was examined in sera from leprosy patients. It was found that the immunological reactions correlated with the clinical spectrum of leprosy; and in multibacillary patients, antibody titres declined in response to successful treatment. The serological patterns were similar to the PGL I patterns, however, the IgG responses towards the sulpholipids were predominant over the IgM responses in the case of the sulpholipid antigens.

Original languageEnglish
Pages (from-to)209-215
Number of pages7
JournalZentralblatt fur Bakteriologie
Volume273
Issue number2
DOIs
Publication statusPublished - 1990

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