TY - JOUR
T1 - Ibero-American Consensus for the Management of Liver Metastases of Soft Tissue Sarcoma
T2 - Updated Review and Clinical Recommendations
AU - Lopes-Brás, Raquel
AU - Muñoz, Paula
AU - Netto, Eduardo
AU - Fernández, Juan Ángel
AU - Serradilla-Martín, Mario
AU - Lozano, Pablo
AU - Esperança-Martins, Miguel
AU - Blanco-Fernández, Gerardo
AU - González-López, José Antonio
AU - Muñoz-Casares, Francisco Cristóbal
AU - Fernandes, Isabel
AU - Asencio-Pascual, José Manuel
AU - Vasques, Hugo
N1 - Publisher Copyright:
© 2025 by the authors.
PY - 2025/4
Y1 - 2025/4
N2 - Liver metastases from soft tissue sarcoma are very rare. The standard treatment for metastatic sarcoma is primarily based on chemotherapy, often with poor results. However, when metastases are confined to the liver and are amenable to surgery or ablative techniques, radical treatment could be an option, keeping patients disease-free and without the need for systemic cytotoxic treatment for long periods of time, with a positive impact on overall survival. A multidisciplinary working group of experts in sarcoma and liver surgery reviewed the literature and available evidence and developed a set of clinical recommendations to be voted and discussed in the I Ibero-American Consensus on the Management of Metastatic Sarcoma, held during the III Spanish-Portuguese Update Meeting on the Treatment of Sarcomas in May 2024. Herein, the voting results of this meeting and the resulting consensus recommendations are presented, and their applicability, strengths, and limitations are discussed.
AB - Liver metastases from soft tissue sarcoma are very rare. The standard treatment for metastatic sarcoma is primarily based on chemotherapy, often with poor results. However, when metastases are confined to the liver and are amenable to surgery or ablative techniques, radical treatment could be an option, keeping patients disease-free and without the need for systemic cytotoxic treatment for long periods of time, with a positive impact on overall survival. A multidisciplinary working group of experts in sarcoma and liver surgery reviewed the literature and available evidence and developed a set of clinical recommendations to be voted and discussed in the I Ibero-American Consensus on the Management of Metastatic Sarcoma, held during the III Spanish-Portuguese Update Meeting on the Treatment of Sarcomas in May 2024. Herein, the voting results of this meeting and the resulting consensus recommendations are presented, and their applicability, strengths, and limitations are discussed.
KW - ablative techniques
KW - liver metastases
KW - liver surgery
KW - oligometastatic disease
KW - retroperitoneal sarcoma
KW - soft tissue sarcoma
UR - http://www.scopus.com/inward/record.url?scp=105003805925&partnerID=8YFLogxK
U2 - 10.3390/cancers17081295
DO - 10.3390/cancers17081295
M3 - Article
AN - SCOPUS:105003805925
SN - 2072-6694
VL - 17
JO - Cancers
JF - Cancers
IS - 8
M1 - 1295
ER -
